Created by @Columbia to be the world's foremost neuroscience institute, we are deciphering the brain — how it develops, works, endures and recovers.
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As we announce the retirement of our codirector Eric Kandel, MD, we celebrate his extraordinary scientific career. Read more about this expert in learning and memory who built bridges between science and the humanities:
zuckermaninstitute.columbia.…
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These words, from neuroanatomy pioneer Ramón y Cajal well over a century ago, remain current. Since his time, explorations of the brain have only revealed it to be more expansive than perhaps Cajal even imagined.
Happy Birthday, Ramón! 🧠
#neuroscience #RamonYCajal
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This isn't a watercolor; it's nerve cells that help move the body. Explore the brain-spine connection in this beautiful image from @AndersMNelson, PhD, of the @ruimcosta lab. As seen in Nature Neuroscience:
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#mentallandscapes
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Congratulations to our very own @IshmailSaboor for being named a @pewtrusts Scholar in the Biomedical Sciences! This honor includes support to "young investigators of outstanding promise in science relevant to the advancement of human health.”
pewtrusts.org/en/projects/pe…
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Congratulations to our own Larry Abbott and co-recipients of the 2022 Gruber Neuroscience Prize! The award recognizes “seminal contributions to computational & theoretical neuroscience,” ever more important as large datasets become central to brain science tinyurl.com/4j9tj4rm
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Congratulations to our very own @ruimcosta on receiving the prestigious Director’s Pioneer Award from @NIH_CommonFund! #NIHHighRisk
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Congratulations to @bjmarlin, named an HMMI Freeman Hrabowski Scholar, who does ground-breaking science while creating a diverse and inclusive lab environment.
Check out what she has to say about the future of science.
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ALT Bianca Jones Marlin quote: "The well-being of scientists is the well-being of science."
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These words, from neuroanatomy pioneer Ramón y Cajal well over a century ago, remain current. Since his time, explorations of the brain have only revealed it to be more expansive than perhaps Cajal even imagined.
Happy Birthday, Ramón! 🧠
#neuroscience #RamonyCajal
ALT "The brain is a world consisting of a number of unexplored continents and great stretches of unknown territory"
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NEWS: @ZuckermanBrain Director and CEO @ruimcosta has been elected to @theNAMedicine!
He is one of four @Columbia scientists elected to the Academy this year. Please join us in congratulating Dr. Costa! 🎉 🔬🏆
Learn more about his work here: zuckermaninstitute.columbia.…
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How many neurons does it take to form a memory? Using cutting-edge techniques, @tgeiller and the @attila_losonczy lab, observed small circuits of cells in the hippocampus forming a spatial map, in real time. The study was published today, in @nature.
bit.ly/3xGzEbI
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Congratulations to @bjmarlin! She was named a Herbert and Florence Irving Assistant Professor of Cell Research at the @ZuckermanBrain today, celebrated for her work on inherited factors that switch genes on and off: a new frontier for cancer research.
bit.ly/3q1Qmi6
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As you enjoy the fireworks tonight, why not take a moment to think about the fireworks happening inside your brain!? 💥
From all of us here @ZuckermanBrain, have a safe and happy #FourthofJuly!
(📸: Neurons firing in the brain of a mouse/Gogos & Losonczy Labs)
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Our own Larry Abbott @Columbia is a co-winner of the 2024 Brain Prize! This @lundbeckfonden award for theoretical and computational neuroscience is shared by Dr. Abbott, @HSompolinsky & @sejnowski. Congrats @cu_neurotheory @HebrewU @Harvard @salkinstitute
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ALT Portrait of Larry Abbott with mathematical symbols forming the outline of a brain.
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We are excited to announce Daphna Shohamy, PhD (@DShohamy) as the Zuckerman Institute's new Associate Director! Learn more about Dr. Shohamy's research and leadership: zuckermaninstitute.columbia.…
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We are delighted to welcome Professor @DShohamy, a leading expert in learning and memory, as our new director and CEO!
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Can trauma become written into our chromosomes and passed on to next generations? Read about Dr. @bjmarlin, one of @ZuckermanBrain's newest principal investigators, and her research into this kind of inheritance and its potential for improving lives.
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Today in Neuron, Columbia neuroscientists unveiled an open-source framework to crank up the rate of neuroscientific discovery by simplifying & expanding use of new data analysis tools: Neuroscience Cloud Analysis As a Service (NeuroCAAS)
cell.com/neuron/fulltext/S08…
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How does your brain choose what to remember and what to forget, to help you find a place you've visited before? The @attila_losonczy lab discovers cells that play a role the consolidation of useful long-term memories in @Nature:
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#neuroscience #research
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(1/6) Most mouse researchers focus on male animals. Briana McRae @BriMcR studies females: how parenthood changes their brains. This grad student in @bjmarlin @itamarkahn labs has an interest in oxytocin and a passion for public engagement. #neuroscience #phd Photos: Thomas Barlow
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Congratulations to our own @bjmarlin for being named among this year’s recipients of @McKnightFdn Scholar Awards, which go to early-career neuroscientists in the midst of establishing their own labs and research careers. Read more!
mcknight.org/news-ideas/2024…
#neuroscience 🧠
ALT Bianca Jones Marlin
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We are delighted to announce that @IshmailSaboor has been named an HMMI Freeman Hrabowski Scholar!
His pathbreaking science is complemented by his commitment to a diverse and inclusive lab culture. He has big plans. Read about them in our Q&A.
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ALT Ishmail Abdus-Saboor quote: "Value mistakes. See them as opportunities to learn. We are here to support each other."
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Human DNA contains copied genes found in no other animal. Neuroscientist @fpolleux, working with the Miller, Hillman and Bruno labs, has found evidence that one duplication helps us learn. Check out our new animation on the team's new @Nature paper:
bit.ly/3pEhVzP
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Congratulations to our own @IshmailSaboor! He’s been named co-winner of @SfNtweets prestigious Young Investigator Award for his pathbreaking research into the neurobiology of tactile sensation. His work may “one day provide better care to those suffering with chronic pain.”
Congratulations to this year’s award and prize recipients for their transformative contributions to the neuroscience field and community.
Learn more about the 2023 award and prize announcements, which will be celebrated at #SfN23.
🔗 bit.ly/475bckS
#neurotwitter
ALT Scientific background. Society for Neuroscience logo. 2023 Award and Prize Announcement.
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We see the harm that systemic, institutional
racism causes to Black Americans.
We oppose and condemn police brutality
and demand accountability. We stand by
our Black colleagues, teachers, students
and neighbors. We care about your
safety and your right to succeed in #STEM.
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Do the experiences of your father leave a mark on your genes? Can trauma be passed down from generation to generation? @ZuckermanBrain neuroscientist @bjmarlin explores these questions to gain a complete picture of genetic inheritance.
Watch now:
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NEW RESEARCH: A @ZuckermanBrain study in mice reveals how the brain builds bridges across time — by firing off bursts of activity that seem random, but in fact make up a complex pattern that, over time, helps the brain link events to form a memory. 👇🏻
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How do creatures ultimately get where they want to go? In @Nature, @RockefellerUniv researchers, with our own @cu_neurotheory Larry Abbott, unveil and model brain circuitry in fruit flies underlying this daily navigational feat!
nature.com/articles/s41586-0…
#neuroscience 🪰
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NEWS: Our own Anthony Fitzpatrick (@FitzpatrickLab) receives $11.3M from @NINDSfunding! Grant will support use of @NobelPrize-winning #cryoEM technology to trace 3D structure of protein tangles linked to #Alzheimers, #CTE and other diseases.
Learn more: ow.ly/FzYD30mb5jm
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Photo of the Week @Columbia
Columbia salutes pioneering neuroscientist Eric Kandel, Nobel laureate and bow-tie aficionado, as he retires at age 92 🧠⭐️
news.columbia.edu/content/th…
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How does a fruit fly decide exactly where to deposit her eggs? In their new @NatureNeuro paper, Drs. Kevin Cury and Richard Axel unveil exquisite neural controls that confer flexible decision-making into even innate sequential behaviors like egg laying:
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Proud to see Zuckerman Institute’s @bjmarlin featured on #BlackInNeuro: blackinneuro.com/profiles/bi…
Looking forward to next week's panels and discussions.
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NEWS: @ZuckermanBrain postdoc @TessaMontague has been selected by the HHMI as a 2019 #HannaGrayFellow!
As one of just 15 fellows selected nationwide, Dr. Montague will have the support to pursue challenging scientific questions at the forefront of her field.
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Scientists @stefanofusi2 and Steven Siegelbaum have found a brain area in mice that may reveal how we can quickly discern a stranger from someone familiar. These new findings in @NeuroCellPress may shed light on disorders affecting #memory.
cell.com/issue/S0896-6273(23…
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Congratulations to our own @bjmarlin, PhD, who was selected by @PopSci amongst the “10 most brilliant scientists in the US” for her work on transgenerational trauma:
popsci.com/science/brilliant…
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What causes the loss of smell, aka anosmia, often experienced by people with COVID-19? New research points to rearranged chromosomes in olfactory neurons. From @LomvardasLab Marianna Zazhytska, @albanakodra and collaborators, published in @CellCellPress tinyurl.com/5n7d4jka
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What makes the experience of color possible? In a new @NatureNeuro paper, a team led by @rudybehnia identifies in fruit flies the kind of brain-cell circuitry that transforms wavelengths of light into perceptions like color. zuckermaninstitute.columbia.…
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Congratulations to our own @bjmarlin and @JasonSynaptic @UUtah for winning a @ChanZuckerberg award! They’ll study how traumatic experiences may become biologically recorded in cells in ways that can be passed to the next generation.
💡 Innovation + 👩🏾🔬🧑🏼🔬 Collaboration = 🧠 Increased understanding of the brain
Meet 64 interdisciplinary teams working to expand our understanding of neuroscience + find treatments for neurodegenerative diseases czi.co/42K4IqJ
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Our own @TessaMontague talks to the @nytimes about her fascination with cuttlefish and their surprising cognitive abilities! 🦑🧠 🦑
nytimes.com/2021/07/09/scien…
#neuroscience #Cephalopod #intelligence
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A newfound cell helps explain why a mouse species is monogamous while its relatives are promiscuous. The findings in @Nature from our own @bendesky and colleagues may reveal treatments for nurturing-associated conditions such as postpartum depression.
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ALT The adrenal glands of a Deer mouse (left) and Oldfield mouse (right), showing the relative size of the zona fasciculata (green) and the novel zona inaudita (red). (Credit: Bendesky lab/Columbia’s Zuckerman Institute).
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On the list of scientists elected this year to the National Academy of Sciences is our own Michael @shadlen!
It’s an honor the NAS bestows on scientists “in recognition of their distinguished and continuing achievements in original research.” tinyurl.com/5yub6p9f
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When deciding what research questions to ask, @Jared_Boyce draws inspiration from issues in the news and his own experiences helping those in crisis. Learn more about his work with mice in the latest installment of The Science Life.
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How do birds remember thousands of spots where they hide food for the winter?
New research on brain cells that turn on in specific locations a step toward seeing what memories look like in our brains. @HannahPaynePhD, Aronov lab. @ScienceMagazine: bit.ly/3B7tdQm
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How does @RafaelNadal keep his eye on the ball? The secret lies in his brain. For this year's @usopen, we explored the #neuroscience of vision, and it comes in at #3 in our most-read stories of 2017: ow.ly/NKSn30hn8PF
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Congratulations to our very own @ruimcosta, part of an international team researching the earliest stages of Parkinson’s that just received a $9M @ASAP_Research grant. bit.ly/2ZAk6JU
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Every move you make is an orchestration of neurons and muscles. New research by @najabam @joshuaiglaser @MarkChurchland and colleagues suggests that the brain micromanages muscles with finer-grained finesse than previously thought possible: zuckermaninstitute.columbia.…
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New Peter Taylor Professor Kenneth Miller at Columbia's @ZuckermanBrain Institute pioneered the use of mathematical models to make sense of how the brain gives us the ability to see: bit.ly/3cmhfI0
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So proud of our own @IshmailSaboor, one of the two @Columbia scientists to receive a @cziscience Diversity Leadership Award!
Learn more here: news.columbia.edu/news/two-c…
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As an animal finds its way around, the brain relies on spatial, sensory, goal-related & other inputs. Our own @attila_losonczy, along with postdoc John Bowler, traced how such info mixes in specific brain regions.
Read their @NeuroCellPress paper! cell.com/neuron/fulltext/S08…
ALT Left: example of VR input Right: cells activity, in a mouse brain, during VR
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There have never been atlases of human brains that detail the locations and types of all of the brain’s 180+ billion cells. A Columbia-led collaboration is devising the means to produce these whole-brain atlases in under a week: zuckermaninstitute.columbia.…
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NEW RESEARCH: How do fruit flies see in color?
Study led by @rudybehnia has identified a brain circuit that drives flies’ ability to see in color — and found that it bears a striking resemblance to the circuitry behind our own capacity for color vision!
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BREAKING NEWS: In a scientific first, @ZuckermanBrain & @CUSEAS engineers translate an individual's thoughts into recognizable, intelligible speech, paving the way for computers to one day communicate directly with the brain. Listen now and learn more: ow.ly/wFoQ30nuQ0v
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Techniques for making brains transparent have revolutionized neuroscience by revealing cells in new ways. See new work from @stelioskosmidis in the Kandel lab on the cover of @CellRepMethods :
cell.com/cell-reports-method…
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Our own Charles Zuker takes listeners (and viewers on YouTube) on an expansive tour of sensation, perception and the irresistible "magic of the brain" in the Huberman Lab Podcast. Have a listen: hubermanlab.com/dr-charles-z…
#neuroscience #perception 🎧
New Huberman Lab Podcast out now: THE BIOLOGY OF TASTE PERCEPTION & SUGAR CRAVING w/Dr Charles Zuker from @Columbia
• Control of Sugar Craving
• Craving Savory (Umami)
• How Thirst Adjusts Hunger
• Food Desire & Avoidance
• How Cells Create a Mind
hubermanlab.com/dr-charles-z…
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Billions of brain cells. Trillions of connections. With a new award from @NIH BRAIN CONNECTS, our own Elizabeth Hillman @HillmanLab aims to trace out this vast wiring diagram at the hub of who we are.
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#neuroscience #BRAINInitiative
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How do hunger, fatigue, mood and other internal states in the brain affect our decisions?
An international team of scientists led by @zuckermanbrain Liam Paninski receives $18.3 million BRAIN Initiative grant to tackle this question!
bit.ly/3D1Cqd0
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NEW RESEARCH: In a scientific first, @ZuckermanBrain and @Columbia's Sarah Woolley and Jordan Moore demonstrate how young songbirds' brains get tuned to the songs they learn while growing up — even if they're raised by a different species. 1/12
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The cells that command muscles to act are typically thought to be simple connections. Now, in @Nature, scientist Stephen Huston reveals they are each capable of triggering far more complex motions than previously thought. @HHMIJanelia
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We were delighted to have Zaila Avant-garde (@Basketballasart) visit @ZuckermanBrain and talk about neuroscience research! A meeting of the minds with Richard Axel, @TessaMontague, @bjmarlin and @IshmailSaboor.
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Please join us in congratulating our own Dr. Rudy Behnia, who has been named a 2018 @McKnightFdn Scholar! Learn more about the award: ow.ly/fZ6B30ktIpe and Dr. Behnia's exciting work on the #neuroscience of vision: ow.ly/vhfR30ktIQ4
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Neuroscientist Katie Insel, PhD, wants to help lawyers and judges better understand what we know and don't know about the brain.
Learn more about the bridges she's building with the criminal justice community in this week's #scilife:
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Building mathematical models of the brain isn’t that complicated, says Kanaka Rajan, PhD, from @cu_neurotheory. Learn more about this @MountSinaiNYC visiting professor who is using comics to attract more people to the field:
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#SciLife
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BREAKING NEWS: High-speed, 3D #SCAPE microscope captures stunning, live videos of nerve cells in action! Discover how @ZuckermanBrain, @CUSEAS and @ColumbiaMed scientists can now view the brain and nervous system in living, moving color: zuckermaninstitute.columbia.…
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Three new @McKnightFdn Scholars from one institution! It's never happened before in this prestigious program’s 46 years of existence. Congratulations to the Zuckerman Institute's own Drs. @ElShamayleh, @VikramGadagkar and @IshmailSaboor
zuckermaninstitute.columbia.…
📢Announcing the 2023 McKnight Scholar Awards🧠
These 10 scholars are committed to solving the most fundamental problems in neuroscience. Learn more about these incredible neuroscientists and the McKnight Endowment Fund for Neuroscience 👇 mcknight.org/news-ideas/2023…
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There, second from the right, is our own @cu_neurotheory Larry Abbott, with this year’s @BrainPrize cowinners @HSompolinsky (right) & @sejnowski (leftmost). HM The King of Denmark handed recipients their medals in Copenhagen on May 30. Read more!
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Yesterday, we had the immense pleasure of celebrating neuroscience as we awarded Professors @HSompolinsky, Terrence Sejnowski, and Larry Abbott with #TheBrainPrize2024 medals for their pioneering contributions to the fields of computational and theoretical neuroscience. Thank you to all who attended, and a special thank you to HM The King of Denmark, the Danish Minister for Higher Education and Science @christinaegelun, @lundbeckfonden, and the chair of our selection committee, Richard Morris.
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The brain can regulate immunity to a striking degree, capable of detecting, boosting & suppressing inflammation. The findings in @Nature from our own Charles Zuker and colleagues may one day help treat many disorders of the immune system.
@NIH @NIAIDNews
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ALT The brain as a thermostat modulating the body's immune response
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Eric Kandel, MD, once wrote: “Has it ever struck you that life is all memory, except for the one present moment that goes by you so quickly you hardly catch it going?” Meet @ZuckermanBrain codirector and Nobel laureate, who has announced his retirement:
zuckermaninstitute.columbia.…
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To create memories from smells, fruit flies depend on a brain region named the mushroom body. Now our own @itsishani @rudybehnia and colleagues have created the first map of the connections between this area and the insects’ visual centers:
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🪰🧠
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NEW RESEARCH: The latest @ZuckermanBrain & @ColumbiaMed study reveals how a small cluster of cells controls memory flow in the brain.
Meet VIP cells: the neurons that help the brain’s internal GPS remember which places matter most: ow.ly/wpC430nwQbr
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NEWS: @ChanZuckerberg Initiative awards $1.5M to @Columbia/@ZuckermanBrain team to create atlas, or reference guide, of the human spine.
Awardee Abbas Rizvi explains how @cziscience's support will spur efforts to combat spinal cord disease & injury: piped.video/cB6LC-1DEkQ
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New research from Siegelbaum's lab @MacaylaDonegan published today in @NatureNeuro reveals cells that remember social interactions, in mice, a potential target to treat social deficits associated with schizophrenia:
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Chickadees can recall the places of thousands of morsels of food to help them survive winter. Now, in @CellCellPress, scientists Dmitriy Aronov, @selmaanchettih, @e_mackevicius and Stephanie Hale have uncovered how:
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#memory #neuroscience 🐦🧠⚡️
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Our inaugural Art in Neuroscience contest, on display for the public in the Greene Science Center lobby, celebrates beautiful images neuroscientists create in their pursuit of knowledge to benefit us all: from elegant spinal neurons to an otherworldy salamander’s brain. 🔬🧠🎨
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This might look like a snapshot of the cosmos, but it's actually the basal ganglia, a brain structure that guides our movements and everyday behavior.
Check out this collaboration between @ruimcosta and researchers at @UCSanDiego:
bit.ly/3fI3C8l
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Summer is here, and we’re celebrating — on the roof! Here’s to our amazing scientists and their pursuit of transformative science. Here’s to awards and honors, to a new director and to the community that makes our institute what it is!
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What if you and your friends could see through each other’s eyes all at once? Today in @Nature, our own Nate Sawtell and Federico Pedraja reveal that elephantnose fish might really do this kind of group sensing with their electro-location sensory system:
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ALT Weakly electric fish, Gnathonemus petersii
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Congratulations to Dr. @bjmarlin for receiving a research grant from the Whitehall Foundation! The grant will help further the Marlin Lab’s work in epigenetics and how experience, such as malnutrition or trauma, can be passed to next generations.
piped.video/watch?v=2WRQXtuw…
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Mouse whiskers are amazing! Like fingers reading Braille, they can feel the shapes of objects. Discover the brain magic that makes this possible in our story describing new @neurocellpress research from @chrisXrodgers.
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We’ve all gotten lost at some point and stumbled on a landmark that helped us find our way. New research by Axel lab’s Walter Fischler-Ruiz (@LabeledLines) published in @NeuroCellPress reveals a mechanism for encoding landmarks in the brain. Learn more:
bit.ly/3Eoi2n4
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Surprise snow storm today @ZuckermanBrain! ⛄️❄️💨
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Congrats to the Cunningham lab for earning the cover in today’s issue of @NeuroCellPress! Read more about their new data-analysis framework, NeuroCASS, which should help researchers extract more insight from the ever-increasing ocean of neuroscience data: cell.com/neuron/issue?pii=S0…
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How Does the Brain Explore?
A new study by @ruimcosta lab, published today in
@CellCellPress reveals brain cells that identify familiar locations, deepening our understanding of how the brain explores new environments.
piped.video/watch?v=ZQX55Wvl…
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Scientists have long known that flows of calcium in brain cells play a role in memory formation.
In a new Science paper, a team of @ZuckermanBrain researchers demonstrate that floods of calcium from within neurons can also influence learning in mice: tinyurl.com/546hw36z
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Meet Richard Axel, the @NobelPrize-winning scientist, @ZuckermanBrain codirector and @Columbia alum whose groundbreaking work has helped scientists decode the science behind our sense of smell:
college.columbia.edu/cct/iss…
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Congratulations to @ZuckermanBrain Daphna Shohamy and Larry Abbott, the new co-directors of @Columbia's Kavli Institute for Brain Science!
bit.ly/3vKTuRu
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How does the brain tune out noises your own body makes? @NatureNeuro study from our own Nate Sawtell offers clues ow.ly/tOlD30bWasq
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Gene linked to both growth and maintenance of brain cells surprises scientists. Eight years of experiments revealed gene's double function, in embryos and adults, now published by @fpolleux lab in @NeuroCellPress !
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The son of artists, @ZabehErfan took a turn toward science when he discovered astronomy. His interest in technology ultimately led him from the cosmic twinkling of stars in space to the electrical twittering of neurons in the brain:
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#scilife #comics 🔭🧠
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Did you know that sleeping is a social experience?
New research from @ZuckermanBrain Steven Siegelbaum's lab suggests that the brain replays social encounters while asleep to remember them.
nature.com/articles/s41586-0…
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Wes Grueber's lab has identified interactions between developing sensory cells that ultimately enable a fly to distinguish a gentle mechanical stimuli, like a breeze, from a painful one, like a hard knock or noxious heat:
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#neuroscience #imaging
ALT In a fruit fly larva’s body wall, sensory cells detect gentle touch (green) and noxious stimuli (magenta)
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No snow days for the Aronov lab! They’re bringing chickadees in from the cold, hoping these birds can teach us how we remember the events of our lives.
piped.video/ymi24mES4TM
❄️🐦❄️ #snowday #birds #Memory
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NEW RESEARCH: Jane Austen's infamously aloof Mr. Darcy had a hard time attracting members of the opposite sex.
The same cannot be said for a #pheromone named for him, called #darcin. 1/5
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For physicist-turned-neuroscientist Larry Abbott, brain cells act a lot like circuits. His research reveals the mental computations that underlie thought.
Watch our latest animation to find out more!
piped.video/km7yx5-85iw
💻🧠🖥️ #neuroscience #animation
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Congratulations @ZuckermanBrain scientists!
Saurabh Vyas (@SaurabhsNeurons), of the Churchland Lab, won the @SfNtweets Donald B. Lindsey Prize in Behavioral Neuroscience, which recognizes an outstanding Ph.D. thesis in behavioral neuroscience: sfn.org/publications/latest-…
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What makes our brains able to see in 3D? Investigating the #neuroscience of vision has been the mission of our own Dr. Carol Mason. Recently, she was elected to @theNASciences ! Join us in congratulating Dr. Mason, and learn more about her work here: ow.ly/qF5q30kbde5
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A study led by @ColumbiaMed's Jennifer Manly (@ManlyEpic) finds that an ability to read and write may offer some protection from dementia.
Learn more in @sciam: scientificamerican.com/artic…
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How do disruptions to the #brain lead to disorders like #schizophrenia or #PTSD? Hear our own Eric Kandel on @scifri as he explores this and other questions in his latest book, The Disordered Mind.
Listen now: ow.ly/msiv30lGbGs
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