@SfNtweets journals #JNeurosci and #eNeuro serve the field by publishing conceptual advances in neuroscience.
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Starting today, there is no longer a fee to submit to The Journal of Neuroscience!
Learn more about submitting to #JNeurosci here: jneurosci.org/content/inform…
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#eNeuro: When @UCLA scientists transferred RNA from #brain cells of trained snails to untrained snails, the animals behaved as if they remembered the trained snails' experiences. @dglanzman
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#JNeurosci: Chari et al. @UCLANeurology designed a novel head-fixed behavioral assay that can be used to investigate behavioral responses to social touch and the underlying brain mechanisms in rodent models of neurodevelopmental conditions like ASD.
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#eNeuro Novel Tools and Methods | Characterization of a Knock-In Mouse Line Expressing a Fusion Protein of κ Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging via CLARITY
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#Dog brain structure varies across breeds and is correlated with specific behaviors, according to new research from @LabHecht published in #JNeurosci.
How humans have shaped the brains of their best friends: bit.ly/2ZAp1o5
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Time-sensitive neurons in the supramarginal gyrus fatigue & skew our subjective perception of time, according to new research from @HayashiMJ @BerkeleyPsych in #JNeurosci.
How the brain creates the experience of time: jneurosci.org/lookup/DOI/10.…
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Male mice more susceptible to stress can pass down their behaviors to offspring via changes in their sperm’s genetic code, according to new #JNeurosci research from @ANeurogirl, @walkerdm79, @EricJNestler et al.
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Dominant & submissive mice have different activity in their dopamine neurons. According to new research in #JNeurosci from @BoXinger4k2017 & @neuronanc2, @wjgao99 et al. @DrexelUniv, inhibiting these neurons can swap the social rank of the rodents. jneurosci.org/lookup/DOI/10.…
ALT schematic of two mice, one dominant and one subordinate, interacting. With box drawn from the prefrontal cortext and showing two dopamine nerve effects.
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"A rat is not a little human, a mouse is not a little rat, and flies are not cheap mice.”
In the latest #eNeuro Opinion article, @L_Genzel discusses factors in rodent studies that will influence whether memory leads to a certain behavior.
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"Another thing I wish I'd known when I started out in the field is just what a huge role there is of just dumb luck — in life in general, but science in particular"
@Nancy_Kanwisher reflects on how the field has progressed during her career in #JNeurosci: jneurosci.org/lookup/DOI/10.…
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#eNeuro: AAVs are a widely used tool in neuroscience allowing researchers to label, trace, and/or manipulate neuronal populations. @jjb930, @ArruCarval_lab, et al. report the need to carefully design & interpret data involving Cre-dependent AAV infection. eneuro.org/lookup/DOI/10.152…
ALT Experimental design and timeline. See Figure 7 in paper for more details
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#JNeurosci: @graham_baum et al used @HumanConnectome data to characterize rate & timing of myelin development. They found evidence for prolonged myelin development into the 30's, reflecting ongoing plasticity for learning & complex cognitive functioning
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#eNeuro | A New Tool for Quantifying Mouse Facial Expressions
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Adult-born neurons keep growing & contributing to brain flexibility long after neurogenesis declines, according to new #JNeurosci research in rats from @DMCBrainHealth @UBCPsych.
How neurons created via neurogenesis differ from infancy-born counterparts: jneurosci.org/lookup/DOI/10.…
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#JNeurosci: The #hippocampus may relay predictions about what we expect to see based on past experience to the visual cortex, suggests a human neuroimaging study @PrincetonNeuro @PsychPrinceton @Yale @NWONieuws @NatEyeInstitute @NIMHgov bit.ly/2uixL5E
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#JNeurosci: #Sleep predicts accumulation of #Alzheimer's pathology #tau & #β-amyloid in human #aging @joe__winer @sleepdiplomat @UCIrvineSOM @UCBerkeleyNeuro @DZNE_de @NIH bit.ly/2INmtwB
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Forget what you saw: a brain region detects when you are about to think of an unwanted memory and alerts other regions to suppress it, according to research recently published in # JNeurosci from @MaityWinky, @Memory_Control et al @mrccbu @SouthwestUni
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#eNeuro: @WJDroogers et al. introduce CAKE, a method for achieving double protein labeling using gene editing in neurons, making it possible to determine localization, interaction & dynamics of endogenous neuronal proteins w/ fluorescence microscopy eneuro.org/lookup/DOI/10.152…
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NEW: #eNeuro has published a special collection of commentaries written by leading neuroscientists in response to @In_Silico_Film, a documentary chronicling Henry Markham's attempt to develop a computer model of the brain. #InSilico
Browse the collection: eneuro.org/collection/episte…
ALT eNeuro logo and title of the special collection, "Epistemological Lessons from the Blue and Human Brain Projects."
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The brains of musicians have stronger structural and functional connections compared to those of non-musicians, regardless of innate pitch ability, according to new #JNeurosci research from @simonleipold, Klein & Jäncke @UZH_en.
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#JNeurosci: Engaging children in conversation from early age could strengthen language regions of developing brain, suggests neuroimaging, @LENAEarlyTalk study by @RachelRRomeo et al @mcgovernmit @BostonChildrens @hgse @Penn @WaltonFamilyFdn @NICHD_NIH bit.ly/2B2mjRl
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Rat mothers in enriching environments have larger offspring, heartier breastmilk, & are more efficient parents, compared to rats in standard lab housing, according to research in #eNeuro from @hollyderosa1 @mindfulrat @caradonnasonny @jordanmarrocco et al.
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#eNeuro: Neuroscientists @DayLabUAB @UABNews have used #CRISPR/Cas9 genome editing technology to regulate genes in the rat brain. Supported by @NIDAnews @NIMHgov bit.ly/2H2s56U
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#eNeuro: @Michelle_Jin1 et al @NIDAnews developed SMART, an open-source extension of the Wholebrain platform, incorporating user-flexibility w/ existing registration & automated cell counting methods to streamline large scale IEG mapping projects in mice. eneuro.org/lookup/DOI/10.152…
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#eNeuro: @MindfulRat et al. challenge the assumption that enhanced rodent lab housing increases trait variability & show that environmental enrichment can improve the current “gold standard” control housing condition without compromising data integrity.
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#JNeurosci: @mazormatan @nadine_dijkstra & @smfleming develop a new machine learning method to decode visibility-related brain activity & find many reported associations between conscious awareness & prefrontal/parietal activity disappear, except the pMFC.
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Rubbing the skin activates an anti-itch neural pathway & can reduce the urge to scratch an itch, according to new #JNeurosci research in mice from @umiamimedicine.
How stroking skin activates touch receptors & recruits spinal cord neurons for itch relief: jneurosci.org/lookup/DOI/10.…
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Brainy Zoom backgrounds for your next meeting: @SfNTweets presents a collection of 10 neuroscience-themed backgrounds from recent #JNeurosci & #eNeuro research, available for download & use in your upcoming virtual gatherings.
See the full collection: bit.ly/2SJatCg
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Celebrating #LeslieUngerleider (1946-2020): In this tribute to her life & prolific career, @ShrutiJapee & @jesstaubert curated several of Dr. Ungerleider's outstanding #JNeurosci papers to illustrate the giant impact she had on the field of neuroscience. jneurosci.org/content/featur…
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How the amygdala responds to viewing negative and subsequent neutral stimuli may impact our daily mood, according to new #JNeurosci research from @puccetti_nikki, @helleryeahz et al. @manateelab.
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Synaptic Connections of Aromatase Circuits in the Medial Amygdala Are Sex Specific
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#JNeurosciSymposia | The Architecture of Human Memory: Insights from Human Single-Neuron Recordings
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#JNeurosci: @CandlerPaige @UTDPainLab et al found CGRP promotes acute & chronic pain in female rodents but little effect on male rodents. This works shows that CGRP targeted therapeutics, already used to treat chronic migraine, could treat pain in women. jneurosci.org/lookup/DOI/10.…
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#eNeuro: @AlexisNJameson @TheErinCalipari @grueterlabvandy et al. @VUmedicine show DA signaling in the NAcc of mice is altered by photoperiod. This occurred in females, showing sex-specific impacts of photoperiod on synapses regulating motivated behaviors.
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#eNeuro: Using a new tool to quantify facial expressions in freely moving mice, @MoeneDr and Larsson @liu_universitet captured different profiles in response to aversive and pleasurable gustatory and somatosensory stimuli.
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#eNeuro: Results from @superrsema, @MelissaHerman4 et al. @Herman_lab_UNC suggest complex interplay between affective state, #alcohol drinking, and the role of prefrontal CRF1+ neurons in mediating these behaviors in rats.
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This watercolor, inspired by the drawings of Ramón y Cajal, shows an oligodendrocyte ensheathing two axons. Drawing by @danielbelchi. For more information, see the article by Sanz-Rodriguez et al. in this week's issue of #JNeurosci bit.ly/2J2xWHE
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#JNeurosci: @danilobenette @rafaelruggiero et al. @usponline investigated neural activities during controllable or uncontrollable stress & identified a distinct pattern of hippocampal-prefrontal cortical activity that predict resistance to future stressors
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New #JNeurosci identifies a fundamental property of hippocampal processing that will enable new insights into how the hippocampus uses visual info to aid other high-level cognitive functions such as memory. @edsilson @corticalpete @Tknapen @Chris_I_Baker
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#eNeuro: Focusing on specific brain regions when studying addiction simplifies research but may omit important insights. @KimbroughNeuro et al. show that the entire mouse brain reorganizes during withdrawal, which may hinder communication between regions.
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#eNeuro Open Source Tools and Methods | An Open Source Platform for Presenting Dynamic Visual Stimuli
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#JNeurosci: Nicotine alters neurotransmission in habit-forming brain region, which may underlie urge to smoke and make it difficult to quit @SahlgrenskaAcad @goteborgsuni @UMmedschool @Hjarnfonden bit.ly/2ttm8IB
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New Dual Perspectives in this week's issue of #JNeurosci explore & debate the evidence for hippocampal neurogenesis in adult humans.
Moreno-Jiménez, Terreros-Roncal, Flor-García et al.: bit.ly/3ckaxlS
Sorrells, Paredes et al.: bit.ly/3fbT5C0
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Your brain pays attention to unfamiliar voices during sleep, according to research in #JNeurosci from @mo_s_ameen, Heib, @christine_blume & @ManuelSchabus. The ability allows the brain to balance sleep with responding to environmental cues. jneurosci.org/lookup/DOI/10.…
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Alcohol alters synchronized brain activity associated with anxiety & fear in the amygdala of mice, but differently for male and female mice, according to new research in #eNeuro from DiLeo, @jmaglab, et al. @TuftsMedSchool.
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New in #JNeurosci: @MarcusWeera @The_Gilp et al. @LSUHealthNO find that inhibiting LH-targeting CeA CRF neurons in stress-avoidant rats prevents stress-driven increases in anxiety-like behavior & alcohol self-administration. Jneurosci.org/lookup/DOI/10.…
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#JNeurosciAnnualSpotlight 2020 | @emilytcowan, @LilaDavachi et al. used fMRI in humans to conclude that the oscillatory pattern of brain activity known as sleep spindles might participate in the restructuring of memory traces during memory consolidation.
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#JNeurosci: Overnight, non-invasive brain stimulation enhances memory storage without disturbing sleep @HRLLaboratories @UNM @DARPA @USArmy bit.ly/2uExXfH
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#eNeuro Open Source Tools & Methods | Krynitsky et al. present the RAT, an open-source machine vision camera & real-time control system for tracking mice based around the @openmvcam camera. #RAT4mice
A cheap, simple & flexible device for tracking rodents: eneuro.org/lookup/DOI/10.152…
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New in #JNeurosci from @tommy_botch and @esfinn: Stable neural patterns that underly how we interpret words grounded in sensory experiences are as unique to us as our fingerprints. @FINNLab_neuro @dartmouth
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Sex-Specific Role for Dopamine Receptor D2 in Dorsal Raphe Serotonergic Neuron Modulation of Defensive Acoustic Startle and Dominance Behavior
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This image provides a sagittal view of white matter fiber tracts in the human brain obtained using Diffusion Spectral Imaging. For more information about the @NIH #BRAIN Initiative, see the article by @NINDSdirector and colleagues in this week's #JNeurosci bit.ly/2usmS10
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#HistoryOfNeuroscience Vol. 11 is now available! Read accounts of the scientific lives that contributed to the field, written by those who lived them.
Tales of brilliance, fantasy, risk, triumph & camaraderie; stories of choice, opportunity & discovery: sfn.org/about/history-of-neu…
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A new #eNeuro study from @TheNeuro_MNI @bic_mni reports that area 8A in the posterior middle frontal gyrus performs the specific cognitive control process of higher order attentional selection between competing visual environmental stimuli.
Read more: eneuro.org/lookup/DOI/10.152…
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Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome
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After a traumatic event, people with decreased activity in the hippocampus experience worse PTSD symptoms, according to new research in #JNeurosci from @busra_to, @vpmurty et al. @Temple_Psych
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#eNeuro: Results from @superrsema, @MelissaHerman4 et al. @Herman_lab_UNC suggest complex interplay between affective state, #alcohol drinking, and the role of prefrontal CRF1+ neurons in mediating these behaviors in rats.
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#eNeuro: Chen et al. @HopkinsMedicine measured receptor mobility in the mouse brain, finding there are different fractions of more and less mobile receptors within individual synapses and that this ratio of receptors can be modulated with stress hormones.
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#JNeurosci: @JA_Balouek @cate_cholamine et al. @PrincetonNeuro found nucleus accumbens neurons initially sensitive to early-life stress remain hypersensitive to stress throughout life in mice. Inhibiting neurons during stress ameliorated hypersensitivity.
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#JNeurosci: Using high-resolution 3D mapping methods in adult mice, Son et al. @yongsookimlab @penn_state found Oxytocin connections with 9 functional brain circuits controlling cognition, brain state, & somatic visceral response.
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In this Editorial, Editor-in-Chief Sabine Kastner introduces the new open peer review model for #JNeurosci. Learn how peer review models have evolved and why sharing anonymous reviewer feedback on published papers can be valuable. doi.org/10.1523/JNEUROSCI.20…
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Read about the life and career of @UtaFrith in the #HistoryOfNeuroscience in Autobiography, Volume 11: sfn.org/about/history-of-neu…
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"We hope this collection will inspire you with how much progress has been made and how much promise there is to make additional advances in understanding neurons, brains, and behavior in the next 50 years."
@MarinaP63’s #50YearsOfNeuroscience Editorial: jneurosci.org/content/40/1/2
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#JNeurosci: @par_boulakis @ADemertzi et al. @PhysioCognGIGA @Giga_CRCivi @frsFNRS found mind blanking is associated w/ widespread decreases in brain activity, specifically in regions involving abilities to produce speech & monitor stream of consciousness.
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New quantitative approaches to volumetric fluorescence labeling will enable rigorous analysis of how synapse distributions change across different brain conditions, including development, learning, and disease.
Novel Tools & Methods in #eNeuro: bit.ly/2sL7A9I
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New #JNeurosci research from @CosmicOmBrain et al. provides a new role of the medial intercalated cells (mICCs), the gatekeeper of amygdala output, in modulating contextual fear in a dynamic and sex-dependent manner.
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Communication between the brain’s auditory and reward circuits is the reason why humans find music rewarding, according to new #JNeurosci research from @zatorrelab et al. @BRAMS_Montreal @theCRBLM
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#eNeuro: AAVs are a widely used tool in neuroscience allowing researchers to label, trace, and/or manipulate neuronal populations. @jjb930, @ArruCarval_lab, et al. report the need to carefully design & interpret data involving Cre-dependent AAV infection. eneuro.org/content/8/6/ENEUR…
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#JNeurosci: Gallo, @pedrobek, @Memory_Control et al. found dopamine release in the medial prefrontal cortex of rats was essential to causing active forgetting of competing memories. Inhibition of D1 receptors impaired forgetting, & activation increased it.
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Contrary to previous theories, fear & anxiety reflect shared neural building blocks, according to new #JNeurosci research from @ajshackman @umdnacs that highlights the need to reevaluate the existing models guiding anxiety research.
Read more: jneurosci.org/lookup/DOI/10.…
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New in #JNeurosci: following up on the discovery that rats favor social reward over drug rewards, the lab of @yavinshaham @NIDAnews @NIH finds sex differences in social behavior: males prefer opposite- over same-sex interactions. jneurosci.org/lookup/DOI/10.…
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People are better at learning & decision-making when trying to avoid harm to others, according to new #JNeurosci research from @LukeLikelihood, @isabellawagnr, @thepsychologist & @ClausLamm.
How learning to avoid harm to others recruits the social brain: jneurosci.org/lookup/DOI/10.…
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#eNeuro Open Source Tools & Methods | @JudeFrie @JakeW_Underhill @DrJKhokhar created OpenVape, an affordable, open-source apparatus for use in behavioral experiments to expose rodents to e-cigarette nicotine vapor.
Read more: eneuro.org/lookup/DOI/10.152…
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#eNeuro from @PozzoMillerLab @UABSOM: Synaptic plasticity in cortico-striatal pathways is hemisphere-dependent, providing a novel mechanistic insight into how cortical neurons distinctly modulate ipsilateral & contralateral subcortical regions.
Read more: bit.ly/2pMghQa
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Postnatal Fluoxetine Treatment Alters Perineuronal Net Formation and Maintenance in the Hippocampus
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#JNeurosci: @russo_eleon et al. developed a statistical approach to investigate dynamics of the prefrontal cortex during suppression of conditioned behaviors, revealing fundamental operational dynamics of the prefrontal cortex for behavioral flexibility.
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New #JNeurosci research from @Singer_Johannes, Cichy, & @martin_hebart @maxplanckpress @FU_Berlin found broad commonalities in the spatiotemporal dynamics & neural representations underlying the perception of photographs & abstract drawings.
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#JNeurosci: Using #optogenetics @agiglesi @alvinnchiu @Flagel_Lab et al. @NGPMichigan confirm the necessity of dopamine neuron activity in the VTA during cue presentation to encode the incentive value of reward cues in male rats.
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New #JNeurosci research from @_zhaoyufei, @AChanales & @KuhlLab demonstrates that in order to remember similar events, the brain exaggerates the difference between them, resulting in divergent brain activity patterns but better memory performance.
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🔓 #eNeuro: 3DMorph Automatic Analysis of Microglial Morphology in Three Dimensions from Ex Vivo and In Vivo Imaging bit.ly/2QKFIgo
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#JNeurosciSymposia | Spinal Interneurons as Gatekeepers to Neuroplasticity after Injury or Disease
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How is taste info encoded? #JNeurosci research reconstructing the synaptic circuitry of taste buds from @courtthewilson et al @taste_and_smell @CUAnschutz, find that taste cannot entirely be carried along nerve fibers dedicated to single taste qualities. jneurosci.org/lookup/DOI/10.…
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New #JNeurosci work from @DMCBrainHealth @UBCPsych shows that the dorsal, prelimbic medial prefrontal cortex aids in both active avoidance of aversive events & withholding of responses to obtain rewards.
Mechanisms underlying avoidance & reward-seeking: jneurosci.org/lookup/DOI/10.…
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Researchers @WSUPullman developed a novel rat model for #cannabis that involves response-contingent delivery of whole-plant extracts using e-vape tech, which will be valuable for studying neural mechanisms that lead to cannabis use & misuse.
#JNeurosci: bit.ly/2Prbbm0
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Mouse models of neurodevelopmental disorders possess unique, sex-specific metabolic dysfunctions, according to a new study in #eNeuro from @menzies_caitlin, @BaptisteLacost3 et al.
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#JNeurosci: Unprecedented view of changes in brain activity created by electrical stimulation could inform individualized stimulation protocols for neuropsychiatric disorders doi.org/10.1523/JNEUROSCI.10…
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#JNeurosci: The brain draws on past experiences to make predictions on the future. How do these predictions influence memory for new experiences? Research from @brynnesherman et al suggest an adaptive role for prediction in regulating when we form memories
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#JNeurosci: Using a combination of behavioral experiments & computational modeling, @AlkisMH et al. show that the brain uses movement errors to directly update controllers that drive motor output, countering predominant theories of sensorimotor adaptation.
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#JNeurosci: How time affects learning, with implications for potential to unlearn associations between drug and reward in addiction @MPC_CompPsych @WCHN_UCL @ucl @dfg_public bit.ly/2voS1lX
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#JNeurosci: @leake_jess, @ZinnRaphael et al. show that detail-poor fear memories formed after insufficient learning time are encoded by fewer neurons that are reactivated in both dangerous & safe contexts in mice, leading to fear in irrelevant situations.
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You never know who will stop by for a chat (or just a quick listen)! @MarinaP63
What kind of intriguing conversations are going to happen at the #SfN24 Meet the Editors today?
Stop by the SfN booth (605) in the exhibit hall to meet with #eNeuro and #JNeurosci editors.
sfn.org/meetings/neuroscienc…
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A new #JNeurosci study from @theCousinLab reveals that an SV2A mutant identified in human #epilepsy loses the ability to control both expression & trafficking of synaptotagmin-1, which is essential for accurate neurotransmitter release.
Read more: jneurosci.org/lookup/DOI/10.…
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A #JNeurosci study in mice from @AsafKeller is first to show that #fentanyl exposure in the womb results in behavioral, circuitry & synaptic effects that last at least to adolescence, and that exposure has lasting effects on synapses in different areas.
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Multitasking performance stems from the speed of information exchange between the putamen & cortical regions of the brain, according to new research from @QldBrainInst @UQPsych in #eNeuro.
The missing piece of the brain's multitasking network: eneuro.org/lookup/DOI/10.152…
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New research in #JNeurosci shows that Purkinje cells have the ability to modulate & filter incoming signals, providing new insights into the learning mechanisms of the cerebellum & brain.
A new learning mechanism at the dendritic level: bit.ly/2Q7wxV2
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Research in #JNeurosci from @prolactingrl @prolactinguy et al. show prolactin, known for its female-specific role in lactation, has a role in the male brain to promote parental care. Father mice w/o prolactin fail to show normal retrieval behavior of pups. jneurosci.org/lookup/DOI/10.…
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Stronger synapses need more energy. Stronger mitochondria produce more power. Do stronger synapses have stronger mitochondria?: bit.ly/2FLzFiF #eNeuro
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#JNeurosci: Gallo, @pedrobek, @Memory_Control et al. found dopamine release in the medial prefrontal cortex of rats was essential to causing active forgetting of competing memories. Inhibition of D1 receptors impaired forgetting, & activation increased it.
jneurosci.org/lookup/DOI/10.…
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#JNeurosci: @ntlichten @KateWassum et al. find a critical circuit between basolateral amygdala & medial OFC affecting decisions & reward evaluation, which may inform new research on substance use disorders & mental illnesses marked by poor decision making.
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