Apropos of the Bryan Johnson heroic dose story:
When I was around 18, I decided to take 5g with two friends, because I was unconvinced by stories I heard of religious ecstasy and bad trips. I measured 5 grams of the mushrooms to prepare a tea, but thought it was most likely not enough so I just chopped and added more without measuring, made the tea, and poured some honey. We drank it in one of my friend's apartment and spent 20 minutes discussing how we simply did not feel anything.
We decided to head to a nearby park that happened to have an exotic flower garden and, once we arrived, it promptly hit. I was overwhelmed by the intensity of colors and the perfume of the flowers. I kept touching my face and the softness of my skin, combined with all other sensations made me fall to the ground, proclaiming universal love. One of my friends was quietly enjoying the moment as this was his third or fourth trip so the novelty had passed and the third one was having a really bad time. He said the flowers were trying to absorb his soul and he was becoming one with them, and that we had to run.
Run he did, he bolted away and we couldn't keep up.
The remaining chill friend and I decided to go for a stroll, hoping to eventually find him. We walked, I don't know for how long, taking in the sights of the city. After a while I started experiencing horrible gastric discomfort from the mushrooms, and begged my friend to stop somewhere so I could use the bathroom. We found a terrifyingly dirty dive bar with dim lights, bought whatever was on the menu, and I went to the bathroom.
The bathroom was painted in a deep purple hue, the floors and walls were covered in black grime and the trashcans were overflowing with waste. There was a single bulb emitting a loud hum and bright white light. I was stunned when I entered, first by the foul smell, second by the fact that I could "see" the noise the lamp was making, I could make out waveforms dancing in front of me, reflecting purple light as the room melted into the whole universe. As I relieved myself, the hum reached a crescendo and I met God. A ball of light overwhelmed me and I saw the entirety of existence. I cried. I flushed the toilet and went outside to meet my friend.
My attempts to explain what just happened were interrupted by him telling me we needed to find our friend, it was getting dark and he didn't answer his phone. We had the idea he probably ran straight to his home, a good hour away by foot. We walked all the way there and what happened before we arrived has since left my memory, but once we did arrive at his home, his younger sister opened the door and yelled at us, asking what did we do to her brother.
Turns out he was in the middle of a panic attack, fully convinced he had died and was now a walking corpse, unable to move on from the world of the living. We spent the next few hours talking to our friend to try and calm him down, with me taking bathroom breaks. His sister had googled that lemon juice would help the buzz come down more quickly, so she forced the poor guy to drink a few bottles of whatever lemon juice the corner store had. It didn't seem to do much other than cause him more discomfort.
As the buzz wore off, I tried to tell the others of my newfound world knowledge and, at some point, my friend's sister told me I should record myself on my phone for when I was sober, because no matter how much she told me I was rambling incoherent nonsense, I wouldn't believe her.
I walked home on my own in the dark, believing myself sober enough and I was stopped dead in my tracks by a giant cat statue from an open air exhibit. I hugged the statue to see if it was real and sat by it, recording my revelations as a voice note on my phone.
The next day I listened to my voice notes, and it was half a dozen ideas about colors, vibrations and perception intertwined with "woaah dude".
I started my physics undergrad the following year.