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Katie Bouman led the creation of an algorithm that helped capture the first ever image of a black hole. We asked her what this breakthrough means for science. For more reaction from other scientists, visit our YouTube channel: go.nature.com/2P3CBNn
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Editorial: The US Department of Health and Human Services proposes to establish a legal definition of whether someone is male or female based on the genitals they are born with. This proposal has no foundation in science and should be abandoned. go.nature.com/2AISMdq
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A Nature paper reports the discovery of the earliest and largest known monumental structure built by the Maya civilization to date. go.nature.com/2U6xxeZ
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A hidden internal structure in Khufu’s Pyramid, the largest pyramid in Giza, Egypt, is uncovered go.nature.com/2A0isPz
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Scientists say that the suggestion that pangolins are the animal source of the coronavirus outbreak seems plausible based on a genetic analysis, but they also caution that the researchers’ work is yet to be published in full. go.nature.com/2HfWLkh
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Today we join #ShutDownSTEM #ShutDownAcademia #Strike4BlackLives. We will not publish Nature today and will instead take time to focus on what we can do better, and plan how we can play our part in eradicating anti-Black racism in academia and STEM. go.nature.com/2MOuDak
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Why Nature supports Joe Biden for US president: He is the nation’s best hope to begin to repair damage to science and the truth — by virtue of his policies and his leadership record in office, as a former vice-president and as a senator. go.nature.com/3lOTBpR
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More than 90 vaccines are being developed against SARS-CoV-2 across the world. At least six groups have begun injecting formulations into volunteers in safety trials. Here is a graphical guide explaining each vaccine design. #COVID19 go.nature.com/3aPtzfX
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Emmanuelle Charpentier and Jennifer Doudna are the winners of the 2020 Nobel Prize in Chemistry for their work developing the revolutionary gene-editing technology CRISPR. go.nature.com/3iymapm
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Editorial: Many PhD students and postdoctoral researchers are overworked and overstressed — and their mental health is suffering because of it. go.nature.com/2JH2Ubw
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Editorial: The potential economic damage from global warming should not be influenced by politics go.nature.com/2jwSf46
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Editorial: Many PhD students and postdoctoral researchers are overworked and overstressed — and their mental health is suffering because of it. go.nature.com/2JH2Ubw
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Decisions on investment and policy are made under the assumption of continuous economic expansion. Thomas W. Murphy Jr writes in @NaturePhysics how physical limits may soon end this phase of development, as foreshadowed by The Limits to Growth. go.nature.com/3voCJ0q
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An artificial intelligence network developed by Google AI offshoot DeepMind has made a gargantuan leap in solving one of biology’s grandest challenges — determining a protein’s 3D shape from its amino-acid sequence. go.nature.com/3o1UmwO
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#onthisday 1869, the first issue of Nature was published. 148 years later, we present a digital copy for you to read go.nature.com/2gYFzCk
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More than 90 vaccines are being developed against SARS-CoV-2 across the world. At least six groups have begun injecting formulations into volunteers in safety trials. Here is a graphical guide explaining each vaccine design. #COVID19 go.nature.com/3aPtzfX
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Hydroxychloroquine shows no substantial antiviral activity in cynomolgus macaques infected with SARS-CoV-2 regardless of the timing of treatment initiation, either before infection, soon after infection or late after infection, according to a Nature paper. go.nature.com/2CSQax4
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Margarita Salas was a courageous role model. She was the first woman to chair a big biomedical research centre, to be president of the Spanish Biochemistry and Molecular Biology Society, and the first to be elected to several academies. go.nature.com/2P6oQPz
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A mutation causing a heritable heart condition has been corrected in preimplantation human embryos using CRISPR–Cas9 go.nature.com/2uktKuD
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Recommended: A free service that suggests relevant papers, based on what you’ve previously read, from all publishers go.nature.com/2ovGM9l
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A study in Nature found 42.5% of the confirmed SARS-CoV-2 infections in Vo', Italy, were asymptomatic. The study also finds no statistically significant difference in the viral load of symptomatic versus asymptomatic infections. #COVID19 go.nature.com/2AfDOOv
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The Human Genome Project published its first draft sequence of the entire human genome 20 years ago. Since then researchers have plunged eagerly into the ‘post-genomic’ era. This week’s Nature cover visualizes the years of research.
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Same-sex sexual behaviour may have evolved repeatedly in mammals, according to a @NatureComms paper. The authors suggest that this behaviour may play an adaptive role in social bonding and reducing conflict. go.nature.com/3LLB1yb
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The discovery of a 13-milllion-year-old skull of an infant ape from Kenya offers new insights into ape evolution go.nature.com/2ftFmcY
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A paper in Nature has determined the crystal structure of the SARS-CoV-2 spike receptor-binding domain (RBD). The findings reveal that the overall ACE2-binding mode of SARS-CoV-2 is nearly identical to that of SARS-CoV. #COVID19 go.nature.com/2yH9tHL
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A Nature paper shows that an antibody isolated from a patient who has recovered from SARS can effectively block SARS-CoV-2 infectivity. Antibodies that can neutralize the virus could help in the development of anti-viral treatments or vaccines. #COVID19 go.nature.com/2ycT261
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Hydroxychloroquine shows no substantial antiviral activity in cynomolgus macaques infected with SARS-CoV-2 regardless of the timing of treatment initiation, either before infection, soon after infection or late after infection, according to a Nature paper. go.nature.com/30PVGsG
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Katie Bouman led the creation of an algorithm that helped capture the first ever image of a black hole. We asked her what this breakthrough means for science. For more reaction from other scientists, visit our YouTube channel: go.nature.com/2P3CBNn
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More than 90 vaccines are being developed against SARS-CoV-2 across the world. At least six groups have begun injecting formulations into volunteers in safety trials. Here is a graphical guide explaining each vaccine design. #COVID19 go.nature.com/2L1KpOc
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“Failure is something that all scientists experience — but it’s hard to tell, looking at our shiny conferences, polished presentations and glossy journals.” go.nature.com/2sxkPrl
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A new virus, originating from Wuhan in China, is quickly spreading across the country and around the world. This video highlights the key things you need to know about the outbreak and how science can help control it. The latest: go.nature.com/2NXGx2T
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Brazilian researchers investigating the cause and extent of wildfires in the Amazon are so afraid for their jobs that they have published their findings in a leading journal anonymously, reports @john_pickrell for @NatureIndex. go.nature.com/2RzE6WU
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More than 90 vaccines are being developed against SARS-CoV-2 across the world. At least six groups have begun injecting formulations into volunteers in safety trials. Here is a graphical guide explaining each vaccine design. #COVID19 go.nature.com/2L1KpOc
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A major biomedical-research organization has for the first time aimed to make financial reparation for the continuing experimental use of cells from Henrietta Lacks, a Black woman whose unknowing donation gave rise to the historic ‘HeLa’ cell line. go.nature.com/3kOfWDW
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A paper in Nature reports that Earth’s vegetation may not be able to continue to absorb human carbon dioxide emissions at current rates, which could accelerate climate change and exacerbate its effects. go.nature.com/2FXUXNi
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The human body is home to trillions of microorganisms that have direct and indirect impacts on health and disease. Our Nature Milestone in Human Microbiota Research provides a historical perspective of the breakthroughs in the field: go.nature.com/2NEOooq
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The first human trial of cells modified with CRISPR gene-editing technology shows that the treatment is safe and lasting. #ResearchHighlight go.nature.com/2z0KP4O
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Editorial: Many PhD students and postdoctoral researchers are overworked and overstressed — and their mental health is suffering because of it. go.nature.com/2JH2Ubw
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As he seeks re-election, US President Donald Trump’s actions in the face of COVID-19 are just one example of the damage he has inflicted on science and its institutions over the past four years, with repercussions for lives and livelihoods. go.nature.com/36BYFcF
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Research in Nature suggests that DNA and RNA co-existed before the emergence of life on Earth. go.nature.com/2C7x3PA
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Stephen Hawking, physicist and icon of science, has died at the age of 76 go.nature.com/2HzucMq
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Distinct patterns on the skin of ocellated lizards are determined by a cellular automaton go.nature.com/2pdd5Yz
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Many doctoral curricula aim to produce narrowly focused researchers rather than critical thinkers. That can and must change, says Gundula Bosch go.nature.com/2Ew4qb9
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Need to stay on top of published research? Try Recommended: go.nature.com/2ovGM9l
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Reopening places such as restaurants, fitness centers, cafes, and hotels carries the highest risk for transmitting SARS-CoV-2, according to a study in Nature. Reducing occupancy in these venues may result in a large reduction in predicted infections. go.nature.com/35sY2B9
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A tiny robot is making leaps and bounds for small-scale locomotion. This soft robot really can walk the walk, as well as being able to roll, jump and swim. This could help it navigate the surprisingly tough terrain inside a human body. Read more: go.nature.com/2Ez8s3m
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A paper in Nature describes a panel of cave art found in Indonesia that depicts human-like figures hunting pigs and buffaloes, dated to at least 43,900 years ago. The panel is the earliest known reported hunting scene from anywhere in the world. go.nature.com/2qIRGMB
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Coronaviruses detected in a small number of pangolins smuggled into China are related to SARS-CoV-2, a Nature paper reports. The degree of similarity isn’t enough to suggest they are the intermediate hosts that are directly involved in the outbreak. go.nature.com/2WM9ELU
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Reopening places such as restaurants, fitness centers, cafes, and hotels carries the highest risk for transmitting SARS-CoV-2, according to a study in Nature. Reducing occupancy in these venues may result in a large reduction in predicted infections. go.nature.com/3pd5oAB
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Two papers in @Nature present a new genome editing technique that enables the insertion, inversion and deletion of long DNA sequences at user-specified genome positions. The approach may provide an easier method of genome editing.
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ALT This is figure 1 from the paper from Patrick Hsu and colleagues, which shows that IS110 mobile genetic elements express a ncRNA that is bound by its encoded recombinase.
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“Scientists have become so accustomed to celebrating only success that we’ve forgotten that most technological advances stem from failure,” writes @drdevangm. go.nature.com/358B4gH
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Images and a short movie have been encoded into the DNA of bacteria using the CRISPR system go.nature.com/2vd8tUB
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Editorial: Institutions have a moral and ethical duty to make scientific research more diverse and representative. Improving the participation of under-represented groups is not just fairer - it could produce better research go.nature.com/2Hw9mgJ
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“Failure is something that all scientists experience — but it’s hard to tell, looking at our shiny conferences, polished presentations and glossy journals.” go.nature.com/2sxkPrl
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An article published in @Nature reports the development of an enzyme that can break down plastics in a week. go.nature.com/38lz8HS
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Editorial: Establishing the economic value of biodiversity is important, but the process must also account for the humanities, of developing countries and of members of indigenous communities. go.nature.com/2lBiwnq
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A handful of genetic and structural analyses have identified a key feature of #COVID19 — a protein on its surface — that might explain why it infects human cells so readily. go.nature.com/3aGqFdQ
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Arguments in favour of allowing COVID-19 to run its course largely unchecked share a misunderstanding about what herd immunity is and how best to achieve it. Nature answers five questions about the controversial idea. go.nature.com/31ICnTb
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A Nature paper shows that there is active replication of coronavirus SARS-CoV-2 in the upper respiratory tract of a group of German patients and suggests that patients may ‘shed’ the virus at high levels during the first week of symptoms. #COVID19 go.nature.com/2waaG9y
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A study in Nature describes the structure of Mpro, the main protease from SARS-CoV-2. Through structure-based screening, the authors identify a number of compounds that can inhibit this protease. go.nature.com/2JTHrLb
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A paper published in Nature reports a battery made from all organic materials, which can be degraded on-demand into environmentally friendly waste products. go.nature.com/3b7t6ZK
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Editorial: Just ten years ago, the idea that microorganisms in the human gut could influence the brain was often dismissed as wild. Not any more. go.nature.com/2SDxDLz
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Editorial: Many PhD students and postdoctoral researchers are overworked and overstressed — and their mental health is suffering because of it. go.nature.com/2JH2Ubw
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Ultra-high-field scanners with 10.5-tesla magnets reveal structures of the human brain that were previously unseen and show promise for clinical diagnosis and treatment. go.nature.com/2zmSBSZ
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“Scientists have become so accustomed to celebrating only success that we’ve forgotten that most technological advances stem from failure,” writes @drdevangm. go.nature.com/358B4gH
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More than a dozen research groups worldwide have started analysing wastewater for the new coronavirus as a way to estimate the total number of infections in a community, given that most people will not be tested. go.nature.com/2wbIpPT
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Liquid can levitate and boats can float upside down in this gravity-defying physics experiment. Researchers discovered a peculiar phenomenon that allows lightweight objects to float on the bottom surface of this liquid, with a kind of reverse-buoyancy.
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#OnThisDay in 1953, James Watson and Francis Crick published a paper describing the structure of DNA for the first time. Nature presents a digital version for readers to enjoy go.nature.com/2qWQkus
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Recommended: A free service that suggests relevant papers, based on what you’ve previously read, from all publishers go.nature.com/2ovGM9l
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Research in Nature suggests that DNA and RNA co-existed before the emergence of life on Earth. go.nature.com/2UniMo4
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A study in Nature found 42.5% of the confirmed SARS-CoV-2 infections in Vo', Italy, were asymptomatic. The study also finds no statistically significant difference in the viral load of symptomatic versus asymptomatic infections. #COVID19 go.nature.com/38wSdm8
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A type of parrot from New Zealand has been surprising scientists with their smart predictions. Research suggests that these birds might be smarter than anyone expected, even outperforming monkeys in some tasks.
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Research in Nature suggests that DNA and RNA co-existed before the emergence of life on Earth. go.nature.com/2MqzH4R
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Editorial: Nature’s biennial PhD survey shows anxiety and depression in graduate students is worsening. The health of the next generation of researchers needs systemic change to research cultures. go.nature.com/2QbGjqO
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Sequencing technologies have completely transformed biomedical research over the last two decades. Explore the major breakthroughs in genomic sequencing in the 21st century with the latest Nature Milestone.
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A Nature paper shows that a SARS-CoV-2 mutation that has become dominant over the course of the pandemic increases virus replication. The findings show the importance of the mutation in viral spread, vaccine efficacy, and antibody therapy. go.nature.com/3dWiFZf
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By the time a person notices the first symptoms of cancer, the disease has often spread too far to be treated successfully. That could change, thanks to a blood test that can detect more than 50 types of cancer, often at an early stage. #ResearchHighlight go.nature.com/2JCxLEN
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This week on the Nature cover: Cancer catalogued. Whole-genome sequences for 38 types of tumour. Browse the issue here: go.nature.com/371CVn8
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Editorial: The discovery of a mitochondrial genome editing is a great achievement — even more so because the team had no such plans when it began the work. go.nature.com/331ULYK
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This week on the Nature cover: The path to flight. Meet the closest relatives to early flying vertebrates. Browse the issue here: go.nature.com/3aislxe
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Studies suggest blood clots appear in 20% to 30% of critically ill COVID-19 patients. Scientists have a few hypotheses to explain the phenomenon, and they are just beginning to launch studies. But they are also scrambling to test clot-curbing medications. go.nature.com/2YGUuIG
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A peculiar bacterial enzyme has allowed researchers to achieve what even the popular CRISPR–Cas9 genome-editing system couldn’t manage: targeted changes to the genomes of mitochondria, cells’ crucial energy-producing structures. go.nature.com/2ZtWSTa
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A paper published in Nature demonstrates the MuZero algorithm from DeepMind, which uses model-based reinforcement learning to achieve superhuman performance in games without knowing anything about their rules. go.nature.com/37KeMFd
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A new study in Nature disproves a long-standing idea that multi-celled animals evolved from a single-celled ancestor resembling a modern sponge cell. Instead, it was probably quite similar to a stem cell. Read the paper here: go.nature.com/2ZqVKwF
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Studies suggest blood clots appear in 20% to 30% of critically ill COVID-19 patients. Scientists have a few hypotheses to explain the phenomenon, and they are just beginning to launch studies. But they are also scrambling to test clot-curbing medications. go.nature.com/2LkURAQ
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A study in Nature reports 2 infected dogs out of 15 households with confirmed cases of #COVID19. Genetic sequences of the viruses from the dogs were identical to the virus detected in the human cases, suggesting human-to-animal transmission of SARS-CoV-2. go.nature.com/3dHWDrO
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An RNA-editing tool that ‘timestamps’ RNA molecules reveals not only which genes in a cell are turned on at any one time, but also when they were turned on. #ResearchHighlight go.nature.com/31zTWoB
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A study published by @NatureNeuro in July shows that 45 languages elicit a shared pattern of neural activity in the brain. go.nature.com/3PjFQ1r
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On the cover this week: Axolotl genome. Salamander sequence sheds light on development and regeneration go.nature.com/2nyOXjc
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As debate rumbles on about how and how much poor statistics is to blame for poor reproducibility, Nature asked influential statisticians to recommend one change to improve science. The common theme? The problem is not our maths, but ourselves go.nature.com/2Ajn1pz
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A study in Nature challenges a long-standing idea that multi-celled animals evolved from a single-celled ancestor resembling a modern sponge cell. Instead, it was probably quite similar to a stem cell. Read the paper here: go.nature.com/2ZqVKwF
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“Failure is something that all scientists experience — but it’s hard to tell, looking at our shiny conferences, polished presentations and glossy journals.” go.nature.com/2sxkPrl
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A Nature paper presents the discovery of bacteria that feed on manganese and use the metal as their source of calories. The study also reveals that the bacteria can use manganese to convert carbon dioxide into biomass. go.nature.com/2CyfRmC
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A Nature paper finds that the determinants of COVID-19 severity seem to stem mostly from host factors such as age, lymphocytopenia, and its associated cytokine storm, whereas viral genetic variation did not significantly affect the outcomes. go.nature.com/2AMftzT
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News & Views: Immune cells called macrophages normally ingest and remove damaged cells. A Nature paper shows they also form a layer that shields mouse joints from damage, which has implications for the treatment of arthritis. go.nature.com/2YQcnB1
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Editorial: Nature’s biennial PhD survey shows anxiety and depression in graduate students is worsening. The health of the next generation of researchers needs systemic change to research cultures. go.nature.com/2QbGjqO
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A study in Nature describes the structure of Mpro, the main protease from SARS-CoV-2. Through structure-based screening, the authors identify a number of compounds that can inhibit this protease. go.nature.com/2RyNJUJ
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Scientific presentations are too often confusing, boring and overstuffed. Here are some suggestions that could make your next conference talk or seminar more enjoyable, engaging and effective. go.nature.com/3hkLdvW
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A Nature paper reports that neurons in the eyes of mice can be reprogrammed to a more youthful state in which they re-acquire the ability to regenerate and restore vision. go.nature.com/3mspFAt
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