Head of Applied Research @OpenAI

San Francisco, CA
At @OpenAI, we believe that AI can accelerate science and drug discovery. An exciting example is our work with @RetroBiosciences, where a custom model designed improved variants of the Nobel-prize winning Yamanaka proteins. Today we published a closer look at the breakthrough. ⬇️
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Excited to see how the public receives GPT-5 ! 🚀
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She said YES !!
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And we love you ❤️
i love the openai team so much
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Mistakes happen. Thank you Ilya, this is inspiring.
I deeply regret my participation in the board's actions. I never intended to harm OpenAI. I love everything we've built together and I will do everything I can to reunite the company.
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Disappointing to see the incentives for the grok team to cheat and deceive in evals. Tl;dr o3-mini is better in every eval compared to grok 3. Grok 3 is genuinely a decent model, but no need to over sell.
once see this you can’t unsee it: the light-blue shading that puts grok-3 over o3-mini is cons@64
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This all happened after midnight, during a company wide holiday. Support was always near unanimous.
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We just released new embeddings at a ridiculously low price! For $40 one can embed all Joe Rogan podcast's transcripts (100k pages of text!) - who will go viral by building a semantic search for it? This is better, and 150x cheaper than previous models! openai.com/blog/new-and-impr…
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Some more napkin math - size of the Internet is ~10^11 pages of text*, this would cost (only?) $50M to embed. Who wants to take on Google?
We just released new embeddings at a ridiculously low price! For $40 one can embed all Joe Rogan podcast's transcripts (100k pages of text!) - who will go viral by building a semantic search for it? This is better, and 150x cheaper than previous models! openai.com/blog/new-and-impr…
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We just open sourced an incredible speech recognition model. It's generally better than me, and works incredibly robustly across background noise, accents and language mixtures, which is really exciting! Let's use it everywhere! openai.com/blog/whisper/
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Replying to @BenjaminDEKR
Surely expressing an opinion on the performance of an unreleased model which you only had access to through working at xAI is against company policies (?)
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Wow, who would’ve thought vision problems would be solved by default through simple scaling
You can ask 4o for a depth map
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Recreating OpenAI reporting structure / social graph based on ♥️s
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I’m on a research visa too that i will lose if i resign. These are details - onwards with the mission! 🚀
I am on an H-1B, in the process of getting my green card and relocating my family to the US. Me and many other colleagues in a similar situation have signed this letter. I do not know what will happen next, but I am confident we will be taken care of. the board should resign.
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OpenAI is nothing without its people!
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Wow, this is one of the bigger firm beliefs i held that got overturned! I wonder how long until we get non slip shoes for ice
New researsh shows ice is slippery because of electrical charges — not pressure and friction. For almost 200 years, the prevailing explanation for ice’s slipperiness was that friction or pressure from a skate, boot, or tire melted a microscopic film of water on the surface, creating a lubricating layer. A new study from Saarland University has overturned that long-standing idea. Instead, the true cause lies in the electric fields generated by molecular dipoles. When any object contacts ice, the partial charges in its own molecules interact with the highly ordered dipole arrangement of water molecules in the ice crystal. This electrostatic tug-of-war loosens the topmost layer of the ice lattice, transforming it into a thin, disordered, quasi-liquid film—without any need for heat or significant pressure. Remarkably, this self-lubrication mechanism works even at temperatures approaching absolute zero, where thermal energy is virtually absent and conventional pressure-melting or frictional heating theories completely break down. In those extreme conditions, ice remains slippery simply because its surface molecules are electrically vulnerable. The discovery fundamentally rewrites our understanding of one of nature’s most familiar phenomena. Beyond settling a centuries-old debate, it has immediate practical implications: from designing better winter tires and non-slip surfaces that actually work on ice, to engineering superior skis, ice skates, and even advanced nanomaterials that perform reliably in cryogenic environments. By revealing the dominant role of intermolecular electric forces, the research opens entirely new avenues for controlling friction and adhesion at the molecular scale—potentially transforming fields from winter sports equipment to aerospace and nanotechnology. ["Cold Self-Lubrication of Sliding Ice", Physical Review Letters, 2025]
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This release is much closer to the original GPT-3 release than the ChatGPT release. A new paradigm, which some will find incredibly valuable for things even we at OpenAI can’t predict. But it’s not a mass product that just works and unlocks new value for everyone effortlessly. I’m confident we will have another ChatGPT moment soon!
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Sometimes there’s a free lunch :)
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Replying to @SullyOmarr
Early feedback was that it’s slow, so we put effort in making it super fast
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ChatGPT briefly overtook Google as a search term !
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Replying to @Dr_Singularity
I’m sorry we failed you and thanks for the patience - hopefully we rectify this soon and make the subscription way more valuable
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Something fun I’m looking to do when we achieve AGI externally
Off-topic: the Witcher 4 looks stunning
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This is incredible !
One nice thing you can do with an interactive world model, look down and see your footwear ... and if the model understands what puddles are. Genie 3 creation.
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4+1=5
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Who thought AGI will likely first be available to anyone who wants it for just $200/month
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Congrats to grok 3 - looks like a great model and a closest competitor to o3!
they omitted o3 from the chart in the livestream for some reason so i added the numbers for you
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The real heroes are the unsung heroes who kept up the website, security and infrastructure through all this! ❤️
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Shipping intelligence too cheap to meter! 🚀
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o3-mini is out - this is both the best and fastest reasoning model!
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“Majorly improved” 😉
Majorly improved GPT-4 Turbo model available now in the API and rolling out in ChatGPT.
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Mysterious… What could this possibly be?!
Livestream in 4.5 hours.
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How can i easily run the 20b model on my phone? I hope someone releases an easy to use app - it would be great to have in places with no service
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Completely wild that the same capability underlying model (and fine tuning) was available through the api for 8 months prior and nobody jumped an opportunity to do this, so we had to build it ourselves. What’s the next UX innovation, waiting to happen in this space?
This is insane. This is what I’ve been alluding to for months now. This is an epochal transformative technology that will soon touch - and radically transform - ALL knowledge work. If most of your work involves sitting in front of a computer, you will be disrupted very, very soon.
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The 20b model is quite possibly the densest packed intelligence created in the universe so far! 🚀
gpt-oss is a big deal; it is a state-of-the-art open-weights reasoning model, with strong real-world performance comparable to o4-mini, that you can run locally on your own computer (or phone with the smaller size). We believe this is the best and most usable open model in the world. We're excited to make this model, the result of billions of dollars of research, available to the world to get AI into the hands of the most people possible. We believe far more good than bad will come from it; for example, gpt-oss-120b performs about as well as o3 on challenging health issues. We have worked hard to mitigate the most serious safety issues, especially around biosecurity. gpt-oss models perform comparably to our frontier models on internal safety benchmarks. We believe in individual empowerment. Although we believe most people will want to use a convenient service like ChatGPT, people should be able to directly control and modify their own AI when they need to, and the privacy benefits are obvious. As part of this, we are quite hopeful that this release will enable new kinds of research and the creation of new kinds of products. We expect a meaningful uptick in the rate of innovation in our field, and for many more people to do important work than were able to before. OpenAI’s mission is to ensure AGI that benefits all of humanity. To that end, we are excited for the world to be building on an open AI stack created in the United States, based on democratic values, available for free to all and for wide benefit.
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We increased rate limits for o1-preview and o1 mini for tier 5. We'll be increasing the limits over the coming weeks, and introducing access to more tiers. 🚀 o1-preview -> 100 requests per minute o1-mini -> 250 requests per minute
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Everyone outside SF in my experience just calls it Chat
What do you call it?
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Every paid ChatGPT user should now have access to OpenAI o1-preview!
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Let us know how we can improve the experience of talking to ChatGPT using voice!
rollout completed early, amazing work by the team! (except for jurisdictions that require additional external review)
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You read the wrong stat. Unemployment rate in Argentina is around 7%. The article refers to “poverty rate”, which is a very different measure. macrotrends.net/global-metri….
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Replying to @pli_cachete
For OpenAI at least for this IMO competition: - No tool use, no calculators, internet, formal proof software, algebra packages - same time limits - the same input to the question as for students; no rewriting it to another more suitable format - only one submission
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Taking what did you get done this week to the extreme. Would it be a new normal for efficient companies to release something new each day?
12 days. 12 livestreams. A bunch of new things, big and small. 12 Days of OpenAI starts tomorrow.
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Things that sound like they are too good to be true can simply just be very very good.
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I predict this will be the most meaningful release so far this year to ChatGPT users!
Deep research is now rolling out to all ChatGPT Plus, Team, Edu, and Enterprise users 🍾
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Go try out o1-mini and don’t be put off by the name - it’s better than o1-preview for some tasks ! It’s really really good and fast
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Yes, this is long overdue and will be addressed soon!
Friend who is a doctor told me everyone in his hospital uses ChatGPT now. Me: “Do you all use o3?” Him: “No, 4o. Isn’t it best to use the latest model? 4 vs 3?” @OpenAI we really gotta fix these model names 🤦‍♂️
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There’s things money can’t buy; Superintelligence
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One of the proudest moments! 🇺🇸
Announcing The Stargate Project The Stargate Project is a new company which intends to invest $500 billion over the next four years building new AI infrastructure for OpenAI in the United States. We will begin deploying $100 billion immediately. This infrastructure will secure American leadership in AI, create hundreds of thousands of American jobs, and generate massive economic benefit for the entire world. This project will not only support the re-industrialization of the United States but also provide a strategic capability to protect the national security of America and its allies. The initial equity funders in Stargate are SoftBank, OpenAI, Oracle, and MGX. SoftBank and OpenAI are the lead partners for Stargate, with SoftBank having financial responsibility and OpenAI having operational responsibility. Masayoshi Son will be the chairman. Arm, Microsoft, NVIDIA, Oracle, and OpenAI are the key initial technology partners. The buildout is currently underway, starting in Texas, and we are evaluating potential sites across the country for more campuses as we finalize definitive agreements. As part of Stargate, Oracle, NVIDIA, and OpenAI will closely collaborate to build and operate this computing system. This builds on a deep collaboration between OpenAI and NVIDIA going back to 2016 and a newer partnership between OpenAI and Oracle. This also builds on the existing OpenAI partnership with Microsoft. OpenAI will continue to increase its consumption of Azure as OpenAI continues its work with Microsoft with this additional compute to train leading models and deliver great products and services. All of us look forward to continuing to build and develop AI—and in particular AGI—for the benefit of all of humanity. We believe that this new step is critical on the path, and will enable creative people to figure out how to use AI to elevate humanity.
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Never bet against OpenAI ❤️
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Today we released #dalle 2 - a model which can generate incredibly impressive images based on a textual description! "A cobra, surfing on a big wave" (Feel free to drop suggestions in the thread - I'll generate and share if they are fun!)
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Billions of people use ChatGPT and it gets better every day - welcome to the future!
This week, ChatGPT is on track to reach 700M weekly active users — up from 500M at the end of March and 4× since last year. Every day, people and teams are learning, creating, and solving harder problems. Big week ahead. Grateful to the team for making ChatGPT more useful and delivering on our mission so everyone can benefit from AI.
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I got fooled by the Reflection 70B announcement. tl;dr - the model performs very badly
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Lots of tweet from almost everyone involved, clarifying the situation and position. But i haven’t heard from three board members at the center of this.
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Love is all you need ! ❤️
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Solving intelligence is not enough. It seems like that as our civilization was bottleneck by intelligence since the Industrial revolution. Intelligence will soon become near free - what will be the next bottlenecks?
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Abundant super intelligence too cheap to meter is well within grasp.
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Together with the team at @RetroBiosciences, we’ve designed novel variants of the Yamanaka factors that achieve a 50x increase in reprogramming efficiency in vitro compared to standard OSKM proteins – a groundbreaking improvement.
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It’s a new state of the art - please try it!
OpenAI quietly launched Whisper V2 in a GitHub commit. github.com/openai/whisper/co…
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The Yamanaka factors (OSKM) are four proteins that have revolutionized biology due to their ability to generate induced pluripotent stem cells (iPSCs) and rejuvenate cells. Unfortunately, they suffer from extremely low levels of reprogramming efficiency.
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Two ways to get GPT-4 access 🤖 1. Sign up to the waitlist (it’ll take a few weeks)🤞 2. Contribute an open source eval (instant access if the PR is approved!) 🎉
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I’d love to collect some feedback. Would you mind responding to this tweet with examples that you were truly IMPRESSED by?
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Your chance to use o3 first hand!
Deep research is now rolling out to all ChatGPT Plus, Team, Edu, and Enterprise users 🍾
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I can’t even imagine what your next thing could possibly be but i trust it’ll make OpenAI just a footnote!
i loved my time at openai. it was transformative for me personally, and hopefully the world a little bit. most of all i loved working with such talented people. will have more to say about what’s next later. 🫡
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Pushing thinking longer with general purpose reasoning models gets us extremely far - Gold IMO medal under the same conditions as humans!
Today, we at @OpenAI achieved a milestone that many considered years away: gold medal-level performance on the 2025 IMO with a general reasoning LLM—under the same time limits as humans, without tools. As remarkable as that sounds, it’s even more significant than the headline 🧵
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Robotics is still very far from being able to do anything close to this. Excellent goal oriented long term planning, agility and replanning when necessary.
This cat has very clear logic. I m shocked
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Replying to @paulg
Keep in mind that 3 is not even a majority of the starting 6 from when this started less than a week ago.
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Yes - my advice to startups is prototype 10 product features - create an eval for 7 that don’t quite work yet and focus on 1 that users love. Then revisit the 7 with each new model release. In stark contrast to spending 3-6 months trying to make other features work reliably.
my new rule - if something *almost* works in an AI product - but doesn’t quite get there, for either cost or model quality / reliability reasons, set a reminder and look at it again in a month chances are it will work now
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Transformers and diffusion models are way too parameter heavy to be practical. A simple temporal sequence Boltzmann machine can simulate the videos of bouncing balls 100,000x more efficiently than Sora. See this gem of a sleeper paper for more details! proceedings.neurips.cc/paper…
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First time proper RL over the space of language! This brings up memories of early days of computers getting better at Go via self play
We're releasing a preview of OpenAI o1—a new series of AI models designed to spend more time thinking before they respond. These models can reason through complex tasks and solve harder problems than previous models in science, coding, and math. openai.com/index/introducing…
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Thank you everyone for the support that you have expressed to me privately. It is very appreciated! 💜 I never knew so many customers, friends, past colleagues, and strangers are watching and cheering for us. Looking forward continuing these amazing relationships wherever i end up! 🚀
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Five in a row this week! Have fun!
Day 3: Something you’ve been waiting for. openai.com/12-days/?day=3
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Amazing investigative work! 👏 😆
Replying to @sama
Five strawberries, but the fifth is not ripe yet 🍓 GPT-5 confirmed within 4-6 weeks 🍓
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The key to our success was the development of GPT-4b micro – a new experimental biology LLM that we developed to test our vision that AI is able to push the frontiers of science.
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Lol, like it was ever about compensation. We got >95% in less than 24 hours, and the compensation never crossed my mind! Can you give us 700 of our amazing colleagues, then we may budge 🚀
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Llama-2-70b costs $59 per million tokens GPT-3.5 Turbo costs $2 per million tokens
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Whoever has ⏸️, ⏹️, ⏩, or ▶️ in their Twitter name is overly radicalized and is difficult to take seriously
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Good luck - humanity will benefit immeasurably if you succeed!
Superintelligence is within reach. Building safe superintelligence (SSI) is the most important technical problem of our​​ time. We've started the world’s first straight-shot SSI lab, with one goal and one product: a safe superintelligence. It’s called Safe Superintelligence Inc. SSI is our mission, our name, and our entire product roadmap, because it is our sole focus. Our team, investors, and business model are all aligned to achieve SSI. We approach safety and capabilities in tandem, as technical problems to be solved through revolutionary engineering and scientific breakthroughs. We plan to advance capabilities as fast as possible while making sure our safety always remains ahead. This way, we can scale in peace. Our singular focus means no distraction by management overhead or product cycles, and our business model means safety, security, and progress are all insulated from short-term commercial pressures. We are an American company with offices in Palo Alto and Tel Aviv, where we have deep roots and the ability to recruit top technical talent. We are assembling a lean, cracked team of the world’s best engineers and researchers dedicated to focusing on SSI and nothing else. If that’s you, we offer an opportunity to do your life’s work and help solve the most important technical challenge of our age. Now is the time. Join us. Ilya Sutskever, Daniel Gross, Daniel Levy June 19, 2024
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For everyone who wants to use o1 effectively - the actual gold is the chains of thought in the blogpost. The amount of detail and rigor helps you appreciate how the algorithm works, and what it may be capable of!
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Replying to @jachiam0
Just wait for the “November surprise“
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Congrats on the "low key research preview" of computer use! ;)
Introducing an upgraded Claude 3.5 Sonnet, and a new model, Claude 3.5 Haiku. We’re also introducing a new capability in beta: computer use. Developers can now direct Claude to use computers the way people do—by looking at a screen, moving a cursor, clicking, and typing text.
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Incredible - keep up the great work!
We’re announcing a research collaboration with @CFS_energy, one of the world’s leading nuclear fusion companies. Together, we’re helping speed up the development of clean, safe, limitless fusion power with AI. ⚛️
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Replying to @apples_jimmy
First time an LLM provider increases prices for a released model. Interesting and unusual
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It was incredible to see the open mindedness of OpenAI employees and leadership, in stark context to ideological dogmatism of the board. We listened, tried to follow along and understand. But it was always just a power grab. Well, only one lesson can be learnt from this. Onwards with the mission!
Many of us have worked with @sama and @gdb for years. They are some of the kindest and highest integrity people there are. Of course we’ll join them. 3 board members, who never engage internally, have had 3 days to tell their story, and they’ve kept quiet. There’s nothing there.
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GPT-4b micro shares the same architecture as GPT-4o, but uses a new training approach with a custom biology dataset that we developed with the goal of enabling scientists to steerably redesign proteins for their needs.
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Great work, may the scaling laws live forever and make us prosper!
The secret behind Gemini 3? Simple: Improving pre-training & post-training 🤯 Pre-training: Contra the popular belief that scaling is over—which we discussed in our NeurIPS '25 talk with @ilyasut and @quocleix—the team delivered a drastic jump. The delta between 2.5 and 3.0 is as big as we've ever seen. No walls in sight! Post-training: Still a total greenfield. There's lots of room for algorithmic progress and improvement, and 3.0 hasn't been an exception, thanks to our stellar team. Congratulations to the whole team 💙💙💙
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Finally!
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In addition to having enhanced reprogramming efficiency, we also find that our reengineered proteins have enhanced DNA damage repair capabilities. More testing is necessary here, but these early results suggest that the proteins may be useful for rejuvenating aged cells.
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I wonder if this will still be a relevant benchmark in a year - thanks for creating it!
Today, we're announcing a preview of ARC-AGI-3, the Interactive Reasoning Benchmark with the widest gap between easy for humans and hard for AI We’re releasing: * 3 games (environments) * $10K agent contest * AI agents API Starting scores - Frontier AI: 0%, Humans: 100%
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Welcome to AI Arctic summer
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The incredible speed with which new models are adopted appears surprises me
GPT-5-Codex already ~40% of traffic for codex! should be the majority some time today.
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This demo from Khan academy is a glimpse into the future of education! Any one out of the tools featured in this video is 🤯 but all of them together honestly make me want to learn school subjects all over again in this fun exploratory way with GPT-4! piped.video/rnIgnS8Susg
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Wow, so much performance baked in!
Our open models are here. Both of them. openai.com/open-models
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Partnering with OpenAI pays off
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Replying to @rishabh16_
Our models are available to anyone. Who will build the next gen search tools and commercialise them effectively?
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It’s getting to the point that the Pro model performs more accurately than some contractors that take weeks to come back, and aren’t able to justify their numbers
Absolutely insane use case for ChatGPT 5 Pro: "help me figure out how much sunlight hits {home address}." Thought for nearly 17 minutes (total across 3 queries), used multiple sources including Project Sunroof, photos from Zillow, historic averages of sunlight in the area, and more. The first result 👇
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The teams at @OpenAI and @RetroBiosciences worked hard for several months to develop GPT-4b micro, and through the process rediscovered several phenomena from text-based models such as scaling laws and in-context learning.
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No GPT-5, but GPT-4o !
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