The leading independent, data-driven voice in psychedelics.
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Pα+ is the insider’s guide to the business, policy and science of psychedelics.
Independent data-driven reporting, analysis and commentary on the psychedelics space: from business and drug development through to policy reform and culture.
psychedelicalpha.com/join
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Elon Musk Comments on Psychedelics
“I think generally people should be open to psychedelics… A lot of people making laws are kind of from a different era. As the new generation gets into political power, I think we will see greater receptivity to the benefits of psychedelics.”
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Hamilton Morris says that trying 5-MeO-DMT has become a kind of status symbol among psychedelic enthusiasts.
However, the "molestation of toads" is not sustainable.
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The definitive source for psychedelic investors.
Breaking news, investor resources, plus exclusive interviews and financing opportunities.
Explore our resources and join our newsletter today: psilocybinalpha.com/
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Yang wants to legalize pot, mushrooms, MDMA for military vets to treat PTSD
nypost.com/2021/05/27/yang-w…
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BREAKING: UK Regulator Urges NHS to Offer Therapy Before Antidepressant Medication
"Millions of people with mild depression in England should be offered therapy, exercise, mindfulness or meditation before antidepressants."
theguardian.com/society/2021…
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BREAKING: Alberta Will Regulate Psychedelics for Use in Therapy
🇨🇦 Canada's 4th largest province, which has a population of 4.5 million, will become the first to regulate psychedelics when rules come into effect in January 2023.
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BREAKING: UK PM Boris Johnson to consider calls to legalise magic mushroom drug psilocybin
bbc.co.uk/news/uk-politics-5…
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How magic mushroom ingredient psilocybin helps patients with depression or PTSD change how they feel, by rewiring the brain with more connections
scmp.com/lifestyle/health-we…
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BREAKING: Bill to Decriminalize Psychedelics in California Passes State Assembly Committee on Public Safety
✅ Aye: 5
❎ No: 3
🗳️ Another success for Scott Wiener's SB 519.
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I'm Giving $100 Million to Psychedelics Research
Blake Mycoskie, founder of TOMs shoes, explains why he's committing a significant sum to support psychedelic research.
newsweek.com/donating-psyche…
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MDMA therapy for PTSD expected to get US approval after latest trial
"US regulators could soon authorise MDMA-assisted psychotherapy for post-traumatic stress disorder after positive results in the largest clinical trial to date"
newscientist.com/article/239…
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HHS Sec. Kennedy suggests he wants to see psychedelic-based therapies available, at least to veterans, within 12 months.
Psychedelic therapies show real promise for veterans and others battling trauma.
We’re accelerating clinical trials at @US_FDA with urgency—and working to ensure safe, science-based access within 12 months. Some therapies can’t wait.
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Study Finds 65% Of Americans With Mental Health Conditions Want Access To Psychedelics
forbes.com/sites/lindseybart…
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BREAKING: California's SB-519, which would decriminalise certain psychedelics, has been set for hearing on 3 August 2022.
The Bill will go before the Assembly Appropriations Committee next month.
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The FDA has accepted Lykos Therapeutics’ (formerly MAPS PBC) New Drug Application for MDMA-assisted therapy for PTSD.
The agency also granted Priority Review and set a target PDUFA date of August 11, 2024, meaning Lykos should expect a decision by that time.
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BREAKING: FDA Rejects Lykos Therapeutics’ MDMA-Assisted Therapy For PTSD
FDA requests additional Phase 3 study from Lykos. The company says it will request a meeting with the agency and urge it to reconsider its decision.
psychedelicalpha.com/news/br…
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BREAKING: State of Kentucky Sets Aside $42 Million for Psychedelic Research
The money, carved out from Opioid Settlement Funds, will be used for psychedelic research, specifically ibogaine for opioid addiction.
The funds will be allocated over seven years.
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Richard Branson calls for 'ending the failed war on drugs'
"...I think as more data becomes available, and as more products are developed, psychedelics-assisted treatment will become commonplace."
virgin.com/branson-family/ri…
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'I took magic mushrooms at 64 and the fog I've lived under my whole life lifted'
"After successful clinical trials of psilocybin for treating depression, there are now calls for its wider use"
telegraph.co.uk/health-fitne…
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DC Voters Decriminalise Psychedelics
Washington, DC Initiative 81 to Decriminalise Psychedelic Plants Has Been Called as a Yes.
Live vote count:
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🗺️ The Psychedelic Sector Landscape 🗺️
A visual overview of the psychedelic sector, organised by market segment or area of focus: from supply right through to delivery.
Interactive version: psilocybinalpha.com/psychede…
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BREAKING: German regulators have green-lit the EU's first psilocybin compassionate access program.
Unlike other countries’ pre-approval pathways, Germany’s does not require case-by-case regulatory approval and may see insurers cover costs.
Details: psychedelicalpha.com/news/ge…
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The U.S. Drug Enforcement Administration (DEA) has transmitted a petition to move psilocybin to Schedule II to the Department of Health and Human Services (HHS).
Read more: psychedelicalpha.com/news/p%…
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BREAKING: MindMed $MMED To Commence Trading on Nasdaq
MindMed will become the second psychedelics company to trade on the Nasdaq.
Ticker symbol $MNMD, expected to list April 27th.
psilocybinalpha.com/news/min…
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MDMA 'will be rolled out in US hospitals by 2024'
MAPS PBC expects to submit a New Drug Application (NDA) to FDA "within months".
dailymail.co.uk/health/artic…
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Johns Hopkins Medicine Receives First Federal Grant for Psychedelic Treatment Research in 50 years
hopkinsmedicine.org/news/new…
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Stroke victims to be given psychedelic drug DMT in groundbreaking study
Vancouver-based Algernon Pharmaceuticals is set to administer microdoses of DMT to those recovering from strokes.
metro.co.uk/2021/02/04/strok…
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"The Department of Veterans Affairs will fund research on the use of psychedelic drugs like MDMA and psilocybin along with therapy to treat post-traumatic stress disorder and depression, the agency announced Friday."
subscriber.politicopro.com/a…
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BREAKING: MindMed Announces Initiation of Phase 1 Clinical Trial of Intravenous DMT
The investigator-initiated study is led by Dr. Matthias Liechti as part of MindMed's ongoing collaboration with the UHB Liechti Lab.
$MNMD $MMED
psilocybinalpha.com/news/min…
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Center for Psychedelic Medicine Established at NYU Langone Health
"New Program Builds on Notable Achievements and Offers First-Ever Dedicated Training Program for Early Career Investigators in the Field"
MindMed $MMED provided $5m in funding.
psilocybinalpha.com/news/cen…
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INVERSE: Magic mushroom study suggests psilocybin may reverse alcohol-induced braind damage
"The psychedelic could also tamp down cravings for alcohol."
inverse.com/mind-body/psiloc…
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Psilocybin: A cure for alcohol addiction and depression?
An interview with @ProfDavidNutt.
heraldscotland.com/news/2376…
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BREAKING: COMPASS Pathways' Phase 2b Trial of Psilocybin for Treatment-Resistant Therapy Published in NEJM
Becomes the largest published psilocybin trial to date.
Quick coverage & analysis to follow.
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“A letter from the Health and Human Services Department discloses the anticipated FDA approval of MDMA and psilocybin treatments.”
theintercept.com/2022/07/26/…
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On Monday evening Roland Griffiths, a pioneer in psychedelic and consciousness research, passed away.
Beyond Griffiths' immense impact on the field of psychedelic research, his legacy includes a Professorship Fund in Psychedelic Research on Secular Spirituality and Well Being.
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Kristen Bell reveals 'psychedelic drugs' helped her cope up with anxiety
geo.tv/latest/350951-kristen…
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Only 2 participants in MAPS' Phase 3 MDMA for PTSD trial reported serious adverse events.
Both were in the placebo group.
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BREAKING: MAPS PBC Files New Drug Application for MDMA-Assisted Therapy for PTSD
Filing marks the first NDA submission for any psychedelic-assisted therapy
psychedelicalpha.com/news/br…
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WHO Gives 5-MeO-DMT Generic Name: Mebufotenin
According to its International Nonproprietary Names for Pharmaceutical Substances (INN) list, the World Health Organisation has given 5-MeO-DMT the nonproprietary name "mebufoteninum".
(Image from Proposed INN list)
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BREAKING: MindMed Announces the Approval of Mescaline Study
$MNMD $MMED
psilocybinalpha.com/news/min…
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Confirmatory Phase 3 Trial of MDMA Therapy for PTSD is “Successful”, Says MAPS
Today, MAPS has announced that its second Phase 3 trial of MDMA-assisted therapy (MDMA-AT) for PTSD confirms prior positive results.
psychedelicalpha.com/news/co…
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🇦🇺 Australia Recognises MDMA and Psilocybin as Medicines
Makes the country in the world to officially recognise the two drugs as medicines.
Our analysis:
psychedelicalpha.com/news/au…
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I Went to Rehab for Alcoholism 18 Times. Only Psychedelics Helped
“Using [psilocybin] four to six times has managed to achieve what the other therapies didn’t do in years.”
vice.com/en/article/g5vzg4/p…
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BREAKING: Canadians Overwhelmingly Support Legal Access to Psilocybin-Assisted Therapy, Poll Reveals
Survey commissioned by @cdnpsychedelic shows >80% of Canadians approve the use of psilocybin therapy for those with end-of-life illnesses.
psilocybinalpha.com/news/can…
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BREAKING: Morgan Stanley Publishes Optimistic Report on Psychedelics
"Early results indicate that psychedelic therapy has the potential to fundamentally reshape how we think about and treat not only mental illness but a host of other conditions as well."
psychedelicalpha.com/news/br…
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BREAKING: The Chopra Foundation and MindMed Enter Into Letter of Intent to Partner on the Future of Psychedelic Medicines & Mental Wellbeing
$MMED $MNMD
psilocybinalpha.com/news/the…
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The Telegraph: Magic mushrooms set to become UK’s ultimate weapon against depression
"A wave of companies have been approved to test psychedelic therapies under new rules drawn up following departure from the EU"
telegraph.co.uk/news/2022/08…
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I am dying of cancer. Black-market psilocybin gave me a new lease on life.
"Mushrooms worked magic on my mental health after a terminal diagnosis. More Canadians should have access to them."
macleans.ca/society/health/b…
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MAPS Completes Second Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD
According to the clinical trial registry entry, 121 participants were recruited and the study was completed on November 2nd.
Slightly ahead of the estimated completion date.
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RFK Jr. Says Access to Psychedelic Therapies to Happen Within 12 Months
He was responding to a question from Rep. Dan Crenshaw (R).
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BREAKING: Australia Approved Psilocybin and MDMA for Use in Treating Depression and PTSD
It will be possible for MDMA to be prescribed for PTSD, and Psilocybin for treatment-resistant depression.
abc.net.au/news/2023-02-03/t…
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New Resource: Psychedelics Drug Development Tracker
A visual overview of the psychedelics drug development landscape, including clinical trial progress status.
psilocybinalpha.com/data/psy…
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California Senate Approves Psychedelic Decriminalization Bill
"California took a step closer to decriminalizing personal possession of various psychedelic drugs as the state Senate passed a landmark bill on Monday."
courthousenews.com/californi…
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Breaking: Health Canada today published notice of intent to amend the Special Access Program (SAP) removing prohibition on access to restricted drugs.
"Certain restricted drugs are now demonstrating potential therapeutic uses, including in Phase II and Phase III clinical trials"
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BREAKING: DEA Withdraws Proposal to Schedule 5 Psychedelic Tryptamines
The challenge was led by co-counsel Matt Zorn and @calyxlaw for @TactogenInc and @MindstateDesign, with many others involved.
This is a remarkable and unprecedented outcome.
5 psychedelic tryptamines, kept off schedule I?
DEA scheduling proceedings—terminated:
“DEA is withdrawing the proposed rule…canceling the public hearing & terminating the pending hearing proceedings”
Unprecedented outcome—a result of extraordinary lawyering by Matt Zorn
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MAPS' Second Phase 3 Study of MDMA-assisted Therapy Reports Positive Results, Paving Way for New Drug Application
psychedelicalpha.com/news/se…
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Lorde Gets Over Stage Fright with MDMA-Assisted Therapy
Speaking with Stephen Colbert on The Late Show, Kiwi singer Lorde said that MDMA-assisted therapy “truly changed the game on my stage fright.”
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BREAKING: First Psychedelic ETF Expected to Launch January 2021 (NEO: $PSYK)
The world’s first Psychedelic ETF looks set to launch in January 2021, providing exposure to publicly-listed, psychedelics-focused life sciences companies in North America.
psilocybinalpha.com/news/fir…
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"Medical psilocybin use should be decided by a patient and their doctor, not the government"
@TheraPsil's Bruce Tobin
theglobeandmail.com/opinion/…
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BREAKING: San Francisco Decriminalizes Entheogenic Plants and Fungi (Psychedelics)
Yesterday, SF made the investigation and arrest of individuals involved with adult use of entheogenic plants among lowest law enforcement priority.
The vote was unanimous, according to Decrim SF.
We are so thrilled to announce that our resolution to decriminalize plants medicines and psilocybin mushrooms passed in San Francisco. May compassion and love prevail here and everywhere! Thank you @DeanPreston and @HillaryRonen for the bravery and intelligence! 🧿🦋✌🏽🌈🙌🏾
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Prince Harry Explains Why Psychedelics Are A 'Fundamental' Part Of His Life
The Duke of Sussex said the drugs are like the "cleaning of a windshield" for him and help "remove life’s filters."
huffingtonpost.co.uk/entry/p…
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'A landmark study shows the main compound in magic mushrooms could rival a leading depression drug'
businessinsider.com/psilocyb…
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California Bill to Decriminalize Psychedelics Held on Call at the State Assembly Committee on Health
Aye: 5
No: 3
#SB519
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"I believe that if people would learn to use LSD's vision-inducing capability more wisely, under suitable conditions, in medical practice and in conjunction with meditation, then in the future this problem child could become a wonderchild."
Happy Birthday, Albert Hofmann.
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🏦 MindMed Uplisting to the Nasdaq
Ticker Symbol: $MNMD
Expected to commence trading: Tuesday April 27th
Details: psilocybinalpha.com/news/min…
$MMED $MMEDF
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BREAKING: Beckley's 5-MeO-DMT Shows Rapid, Durable Antidepressant Effects in Phase 2b Study
Read our analysis of the largest study of 5-MeO-DMT: psychedelicalpha.com/news/be…
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New York Times: The Psychedelic Revolution Is Coming. Psychiatry May Never Be the Same.
nytimes.com/2021/05/09/healt…
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Colorado Looks Set to Decriminalize Psychedelics, Provide Legal Psilocybin Therapy
Proposition 122 apears to have narrowly passed, with 51.03% of counted votes in support of the measure.
However, the count is not yet final.
psychedelicalpha.com/psyched…
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American Medical Association to Issue First New Code for Psychedelic Therapies
A joint press release from COMPASS Pathways and MAPS PBC details the new code.
Full details expected July 2023.
psychedelicalpha.com/news/am…
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MDMA as psychiatric treatment moves closer to US approval
"Long-awaited clinical trial data show psychedelic drug is effective at treating post-traumatic stress disorder in a diversity of people."
nature.com/articles/d41586-0…
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The Scottish government has called for the decriminalisation of all drugs for personal use.
bbc.co.uk/news/uk-scotland-6…
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MindMed collaborators take to the stage to share a first look at their Phase 2 LSD for Anxiety data.
$MNMD #PSYCHSymposium
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Breaking: TheraPsil has secured its 13th exemption from Health Canada to allow access to Psilocybin-assisted therapy for palliative Canadians.
Cc: @TheraPsil
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We're restarting our Interviews series where we speak to folks across the psychedelics space.
Who should we speak to first?
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"A research team from UNC-Chapel Hill, UC San Francisco, Yale, Duke, and Stanford developed a new compound that hits the same brain cell target as psychedelic drugs, triggering long-lasting anti-depressant action without psychedelic effects in mice."
news.unchealthcare.org/2022/…
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Mike Tyson reveals magic mushrooms ‘saved my life’ and hopes psychedelics can now change the world
Former heavyweight champion calls psilocybin an ‘amazing medicine’
independent.co.uk/news/world…
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Diplo says he ran a marathon while on LSD. Experts say he's tripping.
"There isn't notable research to back up any physical boosts Diplo might have gained from taking LSD"
eu.usatoday.com/story/life/h…
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BREAKING: Numinus Wellness To Acquire Neurology Centre of Toronto, Plans to Create Centre for Psychedelic Neurology
$NUMI
psilocybinalpha.com/news/num…
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"I want everyone to appreciate the joy and wonder of every single moment of their lives. We should be astonished that we are here when we look around at the exquisite wonder and beauty of everything."
nytimes.com/interactive/2023…
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BREAKING: North American Psychedelics Index Published:
Which Companies Will Be in $PSYK, the First Psychedelic ETF?
psilocybinalpha.com/news/nor…
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California bill would decriminalize psychedelics, paving the way for medical treatment
"The bill touts the benefits of the drugs and would expunge the criminal records for those already convicted of possession or use of a substance"
theguardian.com/us-news/2021…
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The Economist: "Ketamine, psilocybin and ecstasy are coming to the medicine cabinet"
economist.com/technology-qua…
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1st Berkeley program trains, certifies psychedelic guides
"This fall, 24 people in a first-of-its-kind training program at the year-old UC Berkeley Center for the Science of Psychedelics are learning to safely guide patients’ psychedelic experiences"
news.berkeley.edu/2022/11/10…
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Significant news from $NUMI and MAPS
Numinus and MAPS Public Benefit Corporation announce collaboration agreement to seek approval of MDMA-assisted psychotherapy for PTSD single-arm, open-label trial
psilocybinalpha.com/news/num…
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Finland grants license for psychedelic drug therapy study
"A Canadian drug firm [Clairvoyant] is recruiting 50 people in Finland who suffer from alcohol addiction."
yle.fi/a/3-12676727
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The effort to decriminalize psychedelic drugs in California gained momentum Tuesday after a after a key state Senate committee voted in favor of allowing adults to freely use and possess magic mushrooms and LSD.
courthousenews.com/californi…
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Psychedelics are "fixing people's brains," claims San Francisco's Senator Scott Wiener as he explains Bill SB 519.
Wiener's Bill would see psychedelics decriminalized in the state.
Cc: @Scott_Wiener
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"For the second time, Representative Alexandria Ocasio-Cortez is proposing legislation that would remove barriers to federal research on the therapeutic potential of psychedelics like MDMA and psilocybin."
inverse.com/mind-body/psyche…
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MindMed Announces Inclusion in FTSE Russell Indexes
"as of Friday March 19th, 2021, MindMed has been added to the FTSE Global Micro-Cap Index and the FTSE Total-Cap index."
$MMED $MMEDF
psilocybinalpha.com/news/min…
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FDA Clears MindMed $MNMD IND for MM-120 in Treatment of Generalized Anxiety Disorder
"FDA clearance leads to first commercial IND for LSD, enabling initiation of Phase 2b dose-optimization trial of MM-120 in early 2022"
psilocybinalpha.com/news/fda…
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The VA is undeterred on psychedelics
The Department of Veterans Affairs remains convinced that psychedelic therapy can help treat veterans with post-traumatic stress disorder — and it’s going to try to prove it.
politico.com/newsletters/fut…
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Today, we begin publishing our 2022 Year in Review.
The series kicks off with an Op-Ed from journalist @shayla__love, who is among the most astute observers of the nascent psychedelics industry.
psychedelicalpha.com/news/af…
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MindMed becomes the fourth organisation to receive such FDA Breakthrough Therapy Designation for a psychedelic drug candidate.
Previously, MAPS, Compass Pathways and Usona Institute received the designation, for MDMA and psilocybin (x2), respectively.
MindMed Receives FDA Breakthrough Therapy Designation and Announces Positive 12-Week Durability Data From Phase 2B Study of MM120 for Generalized Anxiety Disorder
finance.yahoo.com/news/mindm…
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The Biden administration is preparing for legal psychedelics within two years
"The letter marks an about face from decades of federal drug policy"
bigthink.com/the-present/bid…
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