Cancer Cell@Cancer_Cell

Cancer Cell provides a high-profile forum for showcasing advances in cancer research, with a strong emphasis on translational research.

 Cambridge, MA, USA
cell.com/cancer-cell
Joined May 2012
You can't miss our June issue, out now! 🎯cell.com/cancer-cell/issue?p…
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Online Now: Tumor-infiltrating lymphocytes: A new hope dlvr.it/T9qW7B
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Online Now: Transcription factor dependencies identify BAF-dependent cancers dlvr.it/T9pXZR
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Online Now: Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity dlvr.it/T9q5VK
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Online Now: The hallmarks of cancer immune evasion dlvr.it/TFFy1H
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The hallmarks of cancer immune evasion dlvr.it/TG8BBS
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Understanding the complexity of p53 in a new era of tumor suppression dlvr.it/T85Rzy
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Discuss “Investigating the interplay between KRAS oncogenic signaling and tumour immune evasion in lung cancer” w/ Julian Downward @JulianDownward @TheCrick @CellSymposia #CSChembio2024. Abstract deadline Aug 16. hubs.li/Q02Kbpdx0
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The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets dlvr.it/TLyB5j
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Engineering cancer’s end: An interdisciplinary approach to confront the complexities of cancer dlvr.it/T9TR8P
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Mitochondrial control of antigen presentation in cancer cells dlvr.it/Sz5BJj
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Online Now: Engineering cancer’s end: An interdisciplinary approach to confront the complexities of cancer dlvr.it/T7yqXS
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Stem-cell-like T cells have a specific entry gate to the tumor dlvr.it/SLvFwh
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In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases dlvr.it/Syqpw5
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Immune cell triads reprogram exhausted CD8+ T cells for effective tumor elimination dlvr.it/T9dfhK
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Stress-induced metastasis: The NET effect dlvr.it/T47r5v
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Online Now: Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment dlvr.it/T38g34
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Online Now: Intratumoral immune triads are required for immunotherapy-mediated elimination of solid tumors dlvr.it/T8b8JK
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Redirecting tumor macrophage activity to fight cancer: Make room for the next era of anti-cancer drugs dlvr.it/S9pT7R
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CAR-T therapy in solid tumors dlvr.it/TKHWmC
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Comprehensive peripheral blood immunoprofiling reveals five immunotypes with immunotherapy response characteristics in patients with cancer dlvr.it/T6xVdw
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We are very proud to present our 2023 Special Issue dedicate to a holistic view of cancer! With 10 Reviews, a Perspective, and our Editorial, we lay out what we see as the future for impactful cancer research. You can read it now: cell.com/cancer-cell/issue?p…
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Online Now: The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets dlvr.it/TL3d9s
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Cancer hallmarks intersect with neuroscience in the tumor microenvironment dlvr.it/SlBzH5
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Online Now: Deciphering the landscape of transcriptional heterogeneity across cancer dlvr.it/Strymq

Deciphering the landscape of transcriptional heterogeneity across cancer

By integrating scRNA-seq datasets across 77 studies and 24 cancer types, in Nature, Gavish et al. uncover recurrent patterns of gene expression that explain a significant proportion of transcriptomic...

cell.com
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From bench to bedside: Single-cell analysis for cancer immunotherapy dlvr.it/S5mld2
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Online Now: Cancer cell states: Lessons from ten years of single-cell RNA-sequencing of human tumors dlvr.it/TCb3kZ
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Online Now: Mitochondrial control of antigen presentation in cancer cells dlvr.it/Sy0MJS
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Online Now: B cells secrete GABA, which provokes a pro-tumor immune microenvironment dlvr.it/SGKHV7
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Online Now: Normal Somatic Mutations in Cancer Transformation dlvr.it/Rm6rYF
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You can now read the February issue of Cancer Cell: cell.com/cancer-cell/issue?p…
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Classifying cancer-associated fibroblasts—The good, the bad, and the target dlvr.it/TDJ8xm
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Online Now: Functional precision oncology: Testing tumors with drugs to identify vulnerabilities and novel combinations dlvr.it/SFz9H4
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Online Now: A unified pan-cancer proteome atlas dlvr.it/TLPtvc
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Bacteria in metastatic sites: Unveiling hidden players in cancer progression dlvr.it/T9Vrt5
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B cells secrete GABA, which provokes a pro-tumor immune microenvironment dlvr.it/SH57Xp
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Online Now: Microbiome and cancer dlvr.it/S7G9sn
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Online Now: Tumor organoid-originated biomarkers predict immune response to PD-1 blockade dlvr.it/S6qWsJ
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Systematic investigation of mitochondrial transfer between cancer cells and T cells at single-cell resolution dlvr.it/SxMlVM
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Online Now: Universal and tissue-specific fibroblasts in chronic inflammation and cancer dlvr.it/TDk9Jz
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Online Now: Spatial oncology: Translating contextual biology to the clinic dlvr.it/TDyf57
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Online Now: In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases dlvr.it/SxjlRX
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Can gut microbes predict efficacy and toxicity of combined immune checkpoint blockade? dlvr.it/S9g5LZ
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A pan-cancer single-cell RNA-seq atlas of intratumoral B cells dlvr.it/TFNVLL
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Online Now: Cancer-associated fibroblast phenotypes are associated with patient outcome in non-small cell lung cancer dlvr.it/T1bxBL
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Online Now: A tumor “personality” test to guide therapeutic decision making dlvr.it/S08GmC
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Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment dlvr.it/T43xQZ
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Intratumoral immune triads are required for immunotherapy-mediated elimination of solid tumors dlvr.it/T9L8n3
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Is resistance to targeted therapy in cancer inevitable? dlvr.it/S5v3Bs
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Low-dose irradiation of the gut improves the efficacy of PD-L1 blockade in metastatic cancer patients dlvr.it/TJZrTP
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Online Now: Pan-cancer human brain metastases atlas at single-cell resolution dlvr.it/TK6FLl
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Tumor organoids: Opportunities and challenges to guide precision medicine dlvr.it/S7mrpY
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The roles of ferroptosis in cancer: Tumor suppression, tumor microenvironment, and therapeutic interventions dlvr.it/T5XG7B
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The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia dlvr.it/T6tmsG
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Online Now: EGFR-activated myofibroblasts promote metastasis of pancreatic cancer dlvr.it/T0jkfK
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Epigenetic enhancement of adoptive T cell immunotherapy dlvr.it/TJbjjs
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Interferon-stimulated neutrophils as a predictor of immunotherapy response dlvr.it/T2jXjj
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Pan-cancer human brain metastases atlas at single-cell resolution dlvr.it/TLw4ZN
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Immunomodulation by targeted anticancer agents dlvr.it/RvJBMq
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Immunotherapy-activated T cells recruit and skew late-stage activated M1-like macrophages that are critical for therapeutic efficacy dlvr.it/T87R4h
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Antihistamines for cancer immunotherapy: More than just treating allergies dlvr.it/SGwhNd
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Online Now: Tumor organoids: Opportunities and challenges to guide precision medicine dlvr.it/S62VKt
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Online Now: Interferon-stimulated neutrophils as a predictor of immunotherapy response dlvr.it/T10XST
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Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment dlvr.it/T16m1Q
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Breaking the mold: Unconventional T cells in cancer therapy dlvr.it/TJRYrN
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Cross-tissue human fibroblast atlas reveals myofibroblast subtypes with distinct roles in immune modulation dlvr.it/TFMfcf
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Node foretold: Cancer cells in lymph node rewire the immune system to enable further metastases dlvr.it/SWQKys
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No rest for the wicked: Tumor cell senescence reshapes the immune microenvironment dlvr.it/SnxHXn
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B cell-rich niches support stem-like CD8+ T cells in cancer microenvironment dlvr.it/Sp5DGT

B cell-rich niches support stem-like CD8+ T cells in cancer microenvironment

Cytotoxic T cells are indispensable for the body’s fight against most cancers. In the current issue of Cancer Cell, Gaglia et al. reveal how changes in the tumor tissue architecture creating niches...

cell.com
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Exploiting the therapeutic implications of KRAS inhibition on tumor immunity dlvr.it/T47JxM
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Dietary modulation of the gut microbiome as an immunoregulatory intervention dlvr.it/SM6tTG
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Online Now: Chemotherapy awakens dormant cancer cells in lung by inducing neutrophil extracellular traps dlvr.it/TLjsMp
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Online Now: Regional CAR T cell therapy: An ignition key for systemic immunity in solid tumors dlvr.it/SPTD98
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IL-1 signaling in aging and cancer: An inflammaging feedback loop unveiled dlvr.it/TGC7LZ
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Online Now: Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy dlvr.it/T7Bd1g
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Online Now: Bacteria in metastatic sites: Unveiling hidden players in cancer progression dlvr.it/T8Sc01
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Online Now: The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia dlvr.it/T5YKv0
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Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer dlvr.it/RdNw2Y
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Online Now: Cross-tissue human fibroblast atlas reveals myofibroblast subtypes with distinct roles in immune modulation dlvr.it/TDTSGq
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ChemoNETosis: A road to tumor therapeutic resistance dlvr.it/Smgt2g
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Cancer-associated fibroblast phenotypes are associated with patient outcome in non-small cell lung cancer dlvr.it/T3zLZH
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Hand in hand to successful immunotherapy: CD8+ T cells and M1-like macrophages swap the baton dlvr.it/T8P3RM
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Online Now: Genomic alterations driving precancerous to cancerous lesions in esophageal cancer development dlvr.it/SzXrS4
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A large-scale snapshot of intratumor heterogeneity in human cancer dlvr.it/RxqMTK
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Senescence in cancer dlvr.it/TM2Fjh
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Online Now: Immune heterogeneity in small-cell lung cancer and vulnerability to immune checkpoint blockade dlvr.it/T2sDL6
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Macrophage-tumor cell intertwine drives the transition into a mesenchymal-like cellular state of glioblastoma dlvr.it/S1xv7g
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The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth dlvr.it/SkrBqz
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Mitochondrial succinate feeds T cell exhaustion in cancer dlvr.it/THzvdY
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Online Now: Neoadjuvant immune checkpoint blockade: A window of opportunity to advance cancer immunotherapy dlvr.it/StyX0V

Neoadjuvant immune checkpoint blockade: A window of opportunity to advance cancer immunotherapy

Among new treatment approaches for patients with cancer, few have accelerated as quickly as neoadjuvant immune checkpoint blockade (ICB). Neoadjuvant cancer therapy is administered before curative-...

cell.com
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A STING operation to expose KRAS and STK11 co-mutated lung cancers dlvr.it/SbDV7z
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Online Now: Rejuvenating dysfunctional T cells in ovarian cancer: CD28 is the license to kill dlvr.it/SBz4bp
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Online Now: Immunomodulation by targeted anticancer agents dlvr.it/Rp6DCw
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Single-cell and spatial profiling identify three response trajectories to pembrolizumab and radiation therapy in triple negative breast cancer dlvr.it/T19FLH
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The mycobiome-immune axis: The next frontier in pancreatic cancer dlvr.it/SKFWLz
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Immune determinants of the pre-metastatic niche dlvr.it/Sl4L58
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Online Now: Patient-derived explants as tumor models dlvr.it/SMkfky
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Online Now: Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers dlvr.it/SzZvYb
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Online Now: Antihistamines for cancer immunotherapy: More than just treating allergies dlvr.it/SDcnDP
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Normal Somatic Mutations in Cancer Transformation dlvr.it/RsZHFg
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Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma dlvr.it/T1DC1t
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