We help crypto & AI startups reach product-market fit. Apply by July 22. Receive $500k funding: alliance.xyz
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Congrats to @Daya_HQ (ALL15) on their $2.4m raise.
Daya lets African businesses bank in USD and pay anyone worldwide.
We raised $2.4M to build the financial operating layer for Africans moving money across borders. Collect locally. Convert smartly. Settle globally.
If you run a business, pay suppliers, work as a freelancer, receive international payments, or move money between countries, you often still face workflows that feel too manual, brittle and expensive. Daya is here to serve you.
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Alliance retweeted
July 14th is a big day for Alliance, our 17th Demo Day, with teams building across stablecoins, prediction markets, AI x crypto, and consumer AI.
Sharing 5 startup metrics ahead of demo day, and keep in mind that every one of these companies started from zero 70 days ago.
• $1.3M ARR
• $250K ARR
• $1M in daily TPV
• $14M in weekly revenue
• 1,000+ daily active users and growing
For the first time, we're opening Demo Day to a broader group of investors + those focused on fintech, crypto and AI. If you are interested in joining our live demo day in NYC, apply below.
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Freeport Markets (@freeportmarkets) gives retail traders buy/sell signals as breaking news happens, allowing users to trade ahead of price moves.
With $60M traded and growing 50% month-over-month, it's clear that a new generation of traders is adopting the tools once reserved for Wall Street.
Congrats on the launch @Bryan__Reed and @Lihong062.
alliance.xyz/launches/freepo…
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We asked @usv's Nikhil (@uninsightful) one question: why NYC?
0:25 How Nikhil joined USV
1:15 Showcasing the USV office
1:54 Lessons learned from @fredwilson
2:50 SF vs NYC from a builders perspective
3:46 USV's investing approach
4:40 NYC's culture & lifestyle
5:42 NY is the place to get customers
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This is the story of four proteins that can rewind aging, and the $4 billion racing to put them inside a human being.
For a century, biologists treated aging like a rusting car. Parts wear out, damage piles up, no reverse gear. A small group now argues that's wrong. Much of what looks like permanent damage, they say, is really a software problem, and software can be rewritten.
Every cell in your body carries identical DNA. What makes one a neuron and another a skin cell is a second layer of information sitting on top, telling each cell which genes to run. The heretical claim is that aging is the slow corruption of that information. And in 2006, a failed orthopedic surgeon named Shinya Yamanaka found four proteins that can retrieve it.
His recipe could take a fully specialized cell and walk it all the way back to a blank, become-anything state. It won him a Nobel. Then scientists found something stranger. Turn the factors on briefly, not long enough to erase a cell's identity, and old mice get younger by every measure, and live about 30% longer. A heart cell stays a heart cell. Just younger.
The boundary with cancer is razor thin. Run the factors too long and you manufacture tumors in bulk. The whole trick depends on not finishing.
Now the money has arrived. Bezos backs @altos_labs. Sam Altman seeded @RetroBio_. Brian Armstrong co-founded @newlimit. David Sinclair's Life Biosciences got through the door first. In January 2026, its eye therapy became the first cellular reprogramming treatment ever cleared for human testing.
The realistic prize isn't immortality. Nobody's living to 300 on an eye injection. It's compression of morbidity, squeezing the sick, declining years at the end of life into a shorter window. The question has finally narrowed. Not "can a cell be made young?" but "can a patient be made well?"
By the early 2030s, we'll know.
Read @QwQiao's essay on the Yamanaka factors below.
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Read the essay.
alliance.xyz/essays/yamanaka…
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Alliance retweeted
I’ll forever be bullish on crypto.
I think we overestimated how quickly crypto would become the next major computing paradigm. A lot of people were searching for the next platform shift and assumed it would be crypto, but in many ways that ended up being AI.
Over the past decade, ton of capital flowed into crypto, and much of it went toward overbuilding. Instead of focusing on a handful of narrow sectors where crypto had a clear advantage, the industry tried to reinvent everything all at once. What we’re seeing now is a natural pullback and consolidation after that period of excess
I don’t think the core thesis is broken by any means. Crypto’s biggest success may not be apps first (even though we have a few), but rails first. As stablecoins, wallets, tokenized stocks and onchain financial infra via neobanks reach every human and eventually every AI agent, crypto becomes the default settlement layer of the internet.
Once those rails are everywhere, many of the ideas that arrived too early like DAOs, decentralized marketplaces, machine to machine payments, and the ideas Vitalik wrote about in the early days of Ethereum may finally have the distribution needed to get it off the ground.
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Less than 24 hours left to apply, get $500,000 and prove everyone wrong → alliance.xyz
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The deadline is tomorrow at midnight pacific.
3 days left to apply to Alliance
‣ Receive up to $500k
‣ Pitch Paradigm, a16z, and Founders Fund at Demo Day
‣ Join a network of 300+ startups
Apply at alliance.xyz/ and tag a founder who needs to see this ↓
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3 days left to apply to Alliance
‣ Receive up to $500k
‣ Pitch Paradigm, a16z, and Founders Fund at Demo Day
‣ Join a network of 300+ startups
Apply at alliance.xyz/ and tag a founder who needs to see this ↓
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The ALL18 Early Application Deadline is 1 Week Away.
Apply at alliance.xyz
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Apply Early by May 27 at alliance.xyz to:
→ Receive $500K in Funding
→ Pitch Tier-1 VCs at Demo Day
→ Join the Alliance Founder Network
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Apply Early by May 28 at alliance.xyz to:
→ Receive $500K in Funding
→ Pitch Tier-1 VCs at Demo Day
→ Join the Alliance Founder Network
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